Progress in neuro-psychopharmacology & biological psychiatry
January 23, 2026
Bruno Romeo, Ewen Kervadec, Baptiste Fauvel et al.
1 citation
The intensity of the psychedelic experience has been shown to be associated with its clinical efficacy. This study aims to investigate the factors that may influence the level of altered consciousness during naturalistic psychedelic use, which serves as a proxy for the intensity of the psychedelic experience. A retrospective online survey was conducted on individuals who reported a psychedelic...
Frontiers in Psychology
2026
Leonardo Christov-Moore, Félix Schoeller, Mathilda Von Guttenberg et al.
Non-pharmacologically induced altered states of consciousness that promote mental health and wellbeing are a growing focus of clinical and basic research. Previous work has revealed the mood-augmenting, belief-altering, and self-transcendent effects of aesthetic-chills-inducing audiovisual stimulation. The current study investigated how a guided loving kindness meditation (LKM) combined with...
Frontiers in Psychology
2026
Human-Friedrich Unterrainer
Altered states of consciousness range from psychotic disintegration to mystical union, with oceanic affectivity - experiences of ego dissolution, boundlessness, and affective merging - constituting a central feature. While such states can be induced by psychedelics, they also occur through trauma, meditative practices, or within compulsive addictive cycles. In addition, oceanic states may offer...
Neuroscience of Consciousness
2026
Valerie van Mulukom
This article proposes a dual-self states framework in which reflective and experiential modes of consciousness are understood as dynamic configurations along a processing continuum. The reflective/experiential self-state corresponds to narrative, denotational, and self-referential consciousness underpinned by default mode network activity. The experiential self state is characterized as an...
Neuroscience of Consciousness
2026
James W. Sanders, Raphaël Millière, Ema Demšar et al.
Psychedelic compound N,N-Dimethyltryptamine (DMT) is renowned for inducing highly immersive experiences, often including encounters with seemingly sentient presences. While such phenomena are well documented, immersion under psychedelics remains conceptually underdefined and phenomenologically underexplored. Here we apply micro-phenomenology to characterize immersion under DMT as a structured...
Nova Science Publishers, Inc. eBooks
2026
Cengiz Mordeniz
Pain Within Altered States of Consciousness challenges conventional assumptions about pain. Rather than treating pain as a simple product of tissue damage, this book presents it as a dynamic construction of conscious experience—shaped by brain networks, attention, emotion, expectation, and the organization of the self. Bringing together anesthesiology, neuroscience, pain medicine, contemplative...
Drug Science, Policy and Law
2026
Jacob S. Aday, Zoe Zong, Jonathan Song et al.
The Five Dimensional Altered States of Consciousness (5D-ASC) Rating Scale is a self-report measure used to characterize changes in consciousness induced by pharmacological (e.g., psychedelics) and non-pharmacological methods (e.g., meditation), and predict clinical outcomes. Although it has been widely used with English-speaking participants, there is no version that has been adapted for...
Digital health
2026
Michael R MacIntyre
As direct-to-consumer ketamine prescriptions obtained via telehealth in the United States, along with psychedelic support, proliferate, some patients are turning to general-purpose chatbots as de facto "therapists" in unmonitored settings. These AI-guided altered-state sessions carry significant ethical, clinical, and legal risks. Current AI tools are not licensed professionals, lack consistent...
HCI International 2025 – Late Breaking Papers
2026
Maria Laura Mele, Hans Rutrecht
The intersection of Virtual Reality (VR) and Altered States of Consciousness (ASCs) represents a notable research domain in experimental and clinical contexts, highlighting the growing interest in how immersive technologies can induce, modulate, and assess non-ordinary cognitive and emotional states. This study examines literature from 2014 to 2024, providing a review of the methodological...