Journal of Education Health and Sport
July 16, 2026
Jakub Bajer, Aleksandra Włodarczyk, Hubert Kulawinek et al.
Background. Post-Traumatic Stress Disorder (PTSD) is an important public health challenge typically treated with trauma-focused psychotherapy and Selective Serotonin Reuptake Inhibitors (SSRIs). However, high rates of residual symptoms associated with these standard treatments have led to a renewed interest in psychedelic-assisted therapies. Aim. This review attempts to examine emerging...
Journal of Psychopharmacology
July 16, 2026
Robert F. Dougherty, Nadav Liam Modlin, Niall M. Mcgowan et al.
Background: When administered alongside monitoring and support, psilocybin has shown promise in the treatment of multiple psychiatric conditions. However, the contribution and nature of participant support in the context of psychedelic trials are much debated. Aims: We sought to further illustrate the structure and format of the monitoring and support used in Compass Pathfinder Ltd (Compass)...
Mindfulness
July 11, 2026
Shilpa Hampole, Haijing Wu Hallenbeck, Joseph Wielgosz et al.
Abstract Objectives Mindfulness-based digital interventions have shown promise for improving health outcomes. The Mindfulness Coach (MC) mobile app was found to improve posttraumatic stress disorder (PTSD) and depression symptoms in a pilot randomized controlled trial (RCT). The current secondary analyses expand on these findings by assessing changes in mindfulness-related processes targeted by...
Scientific Reports
July 11, 2026
Monnica T. Williams, Sonya C. Faber, Jordan Sloshower et al.
This preliminary study explored the effects of MDMA-assisted therapy on trauma symptoms related to discrimination, as measured by the Trauma Symptoms of Discrimination Scale (TSDS). A total of five diverse participants, who experienced multiple types of discrimination (e.g., gender, racial/ethnic, social class, age, sexual orientation), were assessed before and after treatment. A paired-samples...
Journal of Mood and Anxiety Disorders
July 10, 2026
Ashby Boland, Lauren D Reyes, Jenny Black et al.
Nightmares are common after sexual assault and may play an important role in the development of posttraumatic stress disorder (PTSD). However, little research has examined daily temporal associations between nightmares and PTSD symptoms in the acute aftermath of sexual assault. Ecological momentary assessment (EMA) was used to test within- and between-person associations between nightmares and...
Frontiers in Psychiatry
July 8, 2026
Lotem Zvi, Jonathan E. Handelzalts, Danny Horesh et al.
Background Worldwide, there are relatively few specialized inpatient units dedicated to women with histories of childhood sexual abuse (CSA) and comorbid psychiatric disorders. This pilot study examined dissociation and PTSD among women admitted to such a specialized integrative inpatient unit in Israel. We conduct an in-depth analysis of the role of dissociation in these women’s clinical...
The International Journal of Neuropsychopharmacology
July 6, 2026
Shabah M. Shadli, Neda Nasrollahi, Calvin K. Young et al.
BACKGROUND: Neurotic disorders - major depressive disorder (MDD), panic disorder, social anxiety disorder, generalized anxiety disorder, obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), and specific phobia - have differing pharmaceutical profiles. But all, even when resistant to conventional treatment (TR), respond quickly to low dose (0.5-1.0 mg/kg I.M.) ketamine....
Psychedelics
July 1, 2026
Sergio Pérez Rosal, Sonya C. Faber, M. Myriah MacIntyre et al.
Background Racism and discrimination are pervasive social determinants of health, yet mainstream mental health care often fails to address the psychological sequelae of racial trauma, or race-based traumatic stress (RBTS). While psychedelic-assisted therapy (PAT) has re-entered the scientific mainstream, empirical guidance for culturally attuned, integrative care is limited. This study explores...
Therapeutic Advances in Psychopharmacology
July 1, 2026
Karthika Kasiviswanathan, Dinuli Nilaweera, M Morando et al.
Background: 3,4-Methylenedioxymethamphetamine (MDMA)-assisted psychotherapy (MDMA-AP) has demonstrated considerable efficacy in treating post-traumatic stress disorder (PTSD). PTSD and complex PTSD (CPTSD) frequently co-occur with borderline personality disorder (BPD), a complex disorder marked by emotional dysregulation, interpersonal difficulties and abandonment fears - often accompanied by...
BMJ Open
July 1, 2026
Kirsten Morley, Shalini Arunogiri, Katherine L. Mills et al.
INTRODUCTION: The treatment of comorbid post-traumatic stress disorder (PTSD) and alcohol use disorder (AUD) is significantly more challenging than the treatment of either disorder alone. While gold standard evidence-based treatments exist for this comorbidity, clinically significant improvements are only observed in approximately half of clinical trial participants. The use of adjunctive...