Complementary Therapies in Medicine
December 1, 2025
Adam W. Hanley, Yoshio Nakamura, Robert R Edwards et al.
Knee osteoarthritis (KOA) is a prevalent chronic pain condition that significantly impairs quality of life and is often treated with interventions that carry risks or provide limited relief. Reiki, a non-invasive complementary therapy, has shown early promise for pain management but lacks rigorous evaluation among American adults with KOA. This study evaluated the specific efficacy of Reiki and...
JAMA Network Open
April 1, 2025
Aleksandra Zgierska, Robert R Edwards, Bruce P. Barrett et al.
Key Points Question What is the comparative effectiveness of mindfulness-based therapy (MBT) and standard-of-care cognitive behavioral therapy (CBT) among adults with opioid-treated chronic low back pain (CLBP)? Findings In this randomized clinical trial of 770 adults with opioid-treated CLBP, although there were no differences between groups, both the MBT and CBT groups experienced improved...
Frontiers of Architectural Research
January 24, 2024
Zakaria Djebbara, Juliet King, Amir Ebadi et al.
22 citations
This paper takes initial steps towards developing a theoretical framework of contemplative neuroaesthetics through sensorimotor dynamics. We first argue that this new area has been largely omitted from the contemporary research agenda in neuroaesthetics and thus remains a domain of untapped potential. We seek to define this domain to foster a clear and focused investigation of the capacity of...
American Journal of Psychiatry
January 10, 2024
Eric L. Garland, Y. Nakamura, Craig J. Bryan et al.
OBJECTIVE. Evaluate the efficacy of Mindfulness-Oriented Recovery Enhancement (MORE) for past and current military personnel prescribed long-term opioid therapy (LTOT) for chronic pain. METHODS. In a clinical trial, 230 past and current U.S. military personnel prescribed LTOT were randomized (1:1) to MORE or supportive psychotherapy (in-person and then online via Zoom after onset of COVID-19)....
Psychological Medicine
April 1, 2023
Eric L Garland, Spencer T Fix, Justin Hudak et al.
51 citations
Neuropsychopharmacologic effects of long-term opioid therapy (LTOT) in the context of chronic pain may result in subjective anhedonia coupled with decreased attention to natural rewards. Yet, there are no known efficacious treatments for anhedonia and reward deficits associated with chronic opioid use. Mindfulness-Oriented Recovery Enhancement (MORE), a novel behavioral intervention combining...
Science Advances
October 14, 2022
Eric L Garland, Adam W. Hanley, Justin Hudak et al.
39 citations
Self-regulation is instantiated by theta oscillations (4 to 8 Hz) in neurons of frontal midline brain regions. Frontal midline theta (FMΘ) is inversely associated with default mode network (DMN) activation, which subserves self-referential processing. Addiction involves impaired self-regulation and DMN dysfunction. Mindfulness is an efficacious self-regulatory practice for treating addiction,...
JAMA Internal Medicine
February 28, 2022
E. Garland, Adam W. Hanley, Yoshio Nakamura et al.
Key Points Question Does a mindfulness-based intervention reduce comorbid chronic pain and opioid misuse in the primary care setting more than supportive psychotherapy? Findings In this randomized clinical trial that included 250 adults with both chronic pain and opioid misuse, 45.0% of participants receiving Mindfulness-Oriented Recovery Enhancement (MORE) were no longer misusing opioids after...
Neuropsychopharmacology
September 12, 2020
Justin Hudak, Adam W. Hanley, William R. Marchand et al.
46 citations
Endogenous theta stimulation during meditation predicts reduced opioid dosing following treatment with Mindfulness-Oriented Recovery Enhancement.
Frontiers in Psychology
2020
S Shaun Ho, Yoshio Nakamura, James E Swain
15 citations
As interpersonal, racial, social, and international conflicts intensify in the world, it is important to safeguard the mental health of individuals affected by them. According to a Buddhist notion "if you want others to be happy, practice compassion; if you want to be happy, practice compassion," compassion practice is an intervention to cultivate conflict-proof well-being. Here, compassion...
Psychological Assessment
December 1, 2018
Adam W. Hanley, Yoshio Nakamura, Eric L Garland
125 citations
This article details the development of two measures of nondual awareness, the Nondual Awareness Dimensional Assessment-Trait (NADA-T) and the Nondual Awareness Dimensional Assessment-State (NADA-S). Principal component analysis (N = 528) revealed two, interpretable dimensions of the NADA-T: self-transcendence and bliss. Bifactor exploratory structural equation modeling, conducted in three...