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Douglas N. Greve

5 papers in the library · 2,031 citations · publishing 2005-2024

Papers

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Multimodal MRI reveals brainstem connections that sustain wakefulness in human consciousness.

Science Translational Medicine May 1, 2024 Brian L Edlow, Mark Olchanyi, Holly J Freeman et al. 39 citations

Consciousness is composed of arousal (i.e., wakefulness) and awareness. Substantial progress has been made in mapping the cortical networks that underlie awareness in the human brain, but knowledge about the subcortical networks that sustain arousal in humans is incomplete. Here, we aimed to map the connectivity of a proposed subcortical arousal network that sustains wakefulness in the human...

Sustaining wakefulness: Brainstem connectivity in human consciousness

bioRxiv Preprint Server July 13, 2023 Brian L Edlow, Mark Olchanyi, Holly J Freeman et al. preprint

Consciousness is comprised of arousal (i.e., wakefulness) and awareness. Substantial progress has been made in mapping the cortical networks that modulate awareness in the human brain, but knowledge about the subcortical networks that sustain arousal is lacking. We integrated data from ex vivo diffusion MRI, immunohistochemistry, and in vivo 7 Tesla functional MRI to map the connectivity of a...

Mindfulness-Based Stress Reduction, Fear Conditioning, and The Uncinate Fasciculus: A Pilot Study.

Frontiers in Behavioral Neuroscience 2016 Britta K. Hölzel, Vincent Brunsch, Tim Gard et al.

Mindfulness has been suggested to impact emotional learning, but research on these processes is scarce. The classical fear conditioning/extinction/extinction retention paradigm is a well-known method for assessing emotional learning. The present study tested the impact of mindfulness training on fear conditioning and extinction memory and further investigated whether changes in white matter...

Neural mechanisms of symptom improvements in generalized anxiety disorder following mindfulness training

NeuroImage Clinical 2013 Britta K. Hölzel, Elizabeth A Hoge, Douglas N. Greve et al. 285 citations

Mindfulness training aims to impact emotion regulation. Generalized anxiety disorder (GAD) symptoms can be successfully addressed through mindfulness-based interventions. This preliminary study is the first to investigate neural mechanisms of symptom improvements in GAD following mindfulness training. Furthermore, we compared brain activation between GAD patients and healthy participants at...

Meditation experience is associated with increased cortical thickness

Neuroreport November 7, 2005 Sara W. Lazar, Catherine E. Kerr, Rachel H. Wasserman et al. 1,707 citations

Previous research indicates that long-term meditation practice is associated with altered resting electroencephalogram patterns, suggestive of long lasting changes in brain activity. We hypothesized that meditation practice might also be associated with changes in the brain's physical structure. Magnetic resonance imaging was used to assess cortical thickness in 20 participants with extensive...