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Andre Van der Kouwe

3 papers in the library · 39 citations · publishing 2014-2024

Papers

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Multimodal MRI reveals brainstem connections that sustain wakefulness in human consciousness.

Science Translational Medicine May 1, 2024 Brian L Edlow, Mark Olchanyi, Holly J Freeman et al. 39 citations

Consciousness is composed of arousal (i.e., wakefulness) and awareness. Substantial progress has been made in mapping the cortical networks that underlie awareness in the human brain, but knowledge about the subcortical networks that sustain arousal in humans is incomplete. Here, we aimed to map the connectivity of a proposed subcortical arousal network that sustains wakefulness in the human...

Sustaining wakefulness: Brainstem connectivity in human consciousness

bioRxiv Preprint Server July 13, 2023 Brian L Edlow, Mark Olchanyi, Holly J Freeman et al. preprint

Consciousness is comprised of arousal (i.e., wakefulness) and awareness. Substantial progress has been made in mapping the cortical networks that modulate awareness in the human brain, but knowledge about the subcortical networks that sustain arousal is lacking. We integrated data from ex vivo diffusion MRI, immunohistochemistry, and in vivo 7 Tesla functional MRI to map the connectivity of a...

Cannabis use is quantitatively associated with nucleus accumbens and amygdala abnormalities in young adult recreational users.

Journal of Neuroscience April 16, 2014 Jodi M Gilman, John K Kuster, Sang H. Lee et al.

Marijuana is the most commonly used illicit drug in the United States, but little is known about its effects on the human brain, particularly on reward/aversion regions implicated in addiction, such as the nucleus accumbens and amygdala. Animal studies show structural changes in brain regions such as the nucleus accumbens after exposure to Δ9-tetrahydrocannabinol, but less is known about...