Mindfulness
June 18, 2024
Alejandro Interian, Rachael B Miller, Chintan V Dave et al.
Experiences of difficulty (e.g., anxiety, difficult emotions) can occur during mindfulness practice. This study characterized the occurrence of such difficulties, defined as abnormal distress, dysregulation or agitation, among high suicide risk participants during a mindfulness-based intervention. The study also evaluated whether mindfulness difficulties were associated with baseline...
JAMA Psychiatry
April 1, 2024
Nina A Cooperman, Shou-En Lu, Adam W. Hanley et al.
39 citations
Methadone treatment (MT) fails to address the emotion dysregulation, pain, and reward processing deficits that often drive opioid use disorder (OUD). New interventions are needed to address these factors. To evaluate the efficacy of MT as usual (usual care) vs telehealth Mindfulness-Oriented Recovery Enhancement (MORE) plus usual care among people with an OUD and pain. This study was a...
International Journal of Mental Health and Addiction
April 1, 2022
Megan S Chesin, Chintan V Dave, Catherine E Myers et al.
Knowledge of how to effectively prevent suicide attempt (SA) in high suicide risk patients who also misuse opioids is limited. In a subset of data from 36 participants with baseline opioid misuse in a randomized clinical trial testing adjunctive Mindfulness-Based Cognitive Therapy to prevent suicide among high suicide risk Veterans (n=18 per treatment condition), MBCT-S reduced the likelihood...
Behaviour Research and Therapy
October 1, 2021
Megan S Chesin, John G Keilp, Anna Kline et al.
Objective: To test whether Mindfulness-Based Cognitive Therapy to Prevent Suicide (MBCT-S) is associated with improvement in attentional control, an objective marker of suicide attempt. Method: In the context of a randomized clinical trial targeting suicide risk in Veterans, computerized Stroop and emotion Stroop (E-Stroop) tasks were administered 3 times over 6-months follow-up to 135 high...
The Journal of Clinical Psychiatry
August 31, 2021
Alejandro Interian, Megan S Chesin, Barbara Stanley et al.
Objective: This study evaluated whether Mindfulness-Based Cognitive Therapy for Preventing Suicide Behavior (MBCT-S) effectively augmented treatment-as-usual enhanced for suicide prevention (eTAU).Methods: From December 2013 through March 2018, veterans (N = 140) at high risk for suicide were recruited mostly (88.6%) during a suicide-related inpatient admission and randomly assigned to either...
Journal of Substance Abuse Treatment
May 8, 2021
Nina A Cooperman, Adam W. Hanley, Anna Kline et al.
Background: Chronic pain is highly prevalent among people in methadone maintenance treatment (MMT) for opioid use disorder and is known to be an important contributor to treatment discontinuation and opioid relapse. Mindfulness-Oriented Recovery Enhancement (MORE) is one of the few interventions developed and tested as an integrated treatment to simultaneously address both pain and illicit...
Drug and Alcohol Dependence
August 5, 2019
E. Garland, Adam W. Hanley, Anna Kline et al.
Background Methadone maintenance therapy (MMT) is an efficacious form of medication assisted treatment for opioid use disorder (OUD), yet many individuals on MMT relapse. Chronic pain and deficits in positive affective response to natural rewards may result in dysphoria that fuels opioid craving and promotes relapse. As such, behavioral therapies that ameliorate chronic pain and enhance...
Contemporary Clinical Trials
September 2016
Anna Kline, Megan S Chesin, Miriam Latorre et al.
Although suicide ranks 10th as a cause of death in the United States, and 1st among active military personnel, there are surprisingly few evidence-based therapies addressing suicidality, and development of new treatments is limited. This paper describes a clinical trial testing a novel therapy for reducing suicide risk in military veterans. The intervention, Mindfulness-Based Cognitive Therapy...