Using Mindfulness-Based Cognitive Therapy to Prevent Suicide among High Suicide Risk Patients who also Misuse Opioids: A Preliminary Probe of Feasibility and Effectiveness.
Megan S Chesin, Chintan V Dave, Catherine E Myers, Barbara Stanley, Anna Kline, Maureen Monahan, Miriam Latorre, Lauren M Hill, Rachael B Miller, Arlene King, Dianna R. Boschulte, Megan M Sedita, Alejandro Interian
International Journal of Mental Health and Addiction April 1, 2022 DOI: 10.1007/s11469-022-00817-x (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Secondary analysis of a randomized clinical trial Peer reviewed |
|---|---|
| Sample size | 36 |
| Population | Veterans at high suicide risk with baseline opioid misuse |
| Intervention | enhanced treatment as usual (eTAU) |
| Duration | 12-month follow-up |
| Topics | Meditation |
| Keywords | Veterans Opioid misuse |
| Key findings | Among high suicide risk Veterans who misused opioids, adding MBCT-S to enhanced treatment as usual was associated with lower relative risk of suicide attempt (17%) and acute psychiatric hospitalization (42%) over 12 months, and more than halved rates of opioid misuse during follow-up, though only the hospitalization difference was statistically significant. The authors conclude that a larger trial is warranted. |
Abstract
Knowledge of how to effectively prevent suicide attempt (SA) in high suicide risk patients who also misuse opioids is limited. In a subset of data from 36 participants with baseline opioid misuse in a randomized clinical trial testing adjunctive Mindfulness-Based Cognitive Therapy to prevent suicide among high suicide risk Veterans (n=18 per treatment condition), MBCT-S reduced the likelihood of SA and acute psychiatric hospitalization over 12-months follow-up. Those in MBCT-S had a relative risk of 17% and 42% for SA and hospitalization (p=.09, .02), respectively, compared to those receiving enhanced treatment as usual (eTAU) alone. Rates of opioid misuse during follow-up were more than halved with the addition of MBCT-S to eTAU (p=.08). Meanwhile, among trial participants who did not misuse opioids (n=104), RRs of 64% and 77% for SA and hospitalization (p=.28, .33), respectively, were found with MBCT-S compared to eTAU. An MBCT-S trial with greater power is warranted in this population.
Comparable studies
Other randomized controlled trials on meditation, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Alterations in Brain and Immune Function Produced by Mindfulness Meditation Healthy employees in a work environment | 2003 | Randomized controlled trial | n = 41 |
| Prevention of relapse/recurrence in major depression by mindfulness-based cognitive therapy. Recovered recurrently depressed patients | 2000 | Randomized controlled trial | n = 145 |
| Open hearts build lives: Positive emotions, induced through loving-kindness meditation, build consequential personal resources. Working adults | 2008 | Randomized controlled trial | n = 139 |
| Short-term meditation training improves attention and self-regulation Undergraduate Chinese students | 2007 | Randomized controlled trial | n = 40 |
| Mindfulness-Based Cognitive Therapy for Depression: Replication and Exploration of Differential Relapse Prevention Effects. Recovered recurrently depressed patients | 2004 | Randomized controlled trial | n = 73 |
Citations in the library
Cites 9
- Mindfulness: A proposed operational definition. Clinical Psychology Science and Practice 2004
- Mindfulness‐based approaches: are they all the same? Journal of Clinical Psychology January 19, 2011
- Mindfulness-based cognitive therapy for preventing relapse in recurrent depression: A randomized dismantling trial. Journal of Consulting and Clinical Psychology December 3, 2013
- Mindfulness-based cognitive therapy for depression. Industrial Psychiatry Journal October 29, 2024
- Putting mindfulness-based cognitive therapy to the test in routine clinical practice: A transdiagnostic panacea or a disorder specific intervention? Journal of Psychiatric Research October 2021
and 4 more in the library