Arlene King

2 papers in the library · publishing 2024

Papers

Initial evaluation of a personalized advantage index to determine which individuals may benefit from mindfulness-based cognitive therapy for suicide prevention.

Behaviour Research and Therapy December 1, 2024 Catherine E Myers, Chintan V Dave, Megan S Chesin et al.

A treatment matching algorithm was developed to predict which Veterans at high risk for suicide would benefit more from Mindfulness-Based Cognitive Therapy for suicide prevention (MBCT-S) versus enhanced treatment-as-usual (eTAU). Using data from a randomized clinical trial with 140 Veterans, random forest models predicted risk of a suicidal event within 12 months. The model for MBCT-S was slightly more accurate than for eTAU. Key predictors for MBCT-S included PTSD diagnosis, neurocognitive performance, prior residential treatment, and non-suicidal self-injury; for eTAU, past-year hospitalizations, therapy visits, suicidal ideation severity, and attentional control were important. Fewer suicidal events occurred among those assigned to their algorithm-indicated optimal treatment, suggesting the approach may improve outcomes, but further research is needed.

DOI: 10.1016/j.brat.2024.104637 Full text Mindfulness Machine learning Precision medicine Suicide prevention +1

Examining the Occurrence and Clinical Impact of Difficult Experiences that Emerge during a Mindfulness-Based Intervention among Individuals at High-Risk of Suicide.

Mindfulness June 18, 2024 Alejandro Interian, Rachael B Miller, Chintan V Dave et al.

Among adults at high risk of suicide who took part in a mindfulness-based therapy, 18% experienced distress, dysregulation, or agitation during practice, most often anxiety or hallucinations. Those who had such difficulties showed some diagnostic differences at baseline but were not at significantly greater risk of a suicidal event or psychiatric hospitalization over a 12-month follow-up. No suicide attempts occurred among the 9 participants who experienced mindfulness difficulty, compared to 5 attempts among those who did not. The findings suggest that although difficulties during mindfulness are common, they do not increase the risk of serious clinical outcomes in this high-risk population.

DOI: 10.1016/j.cpr.2019.01.001 Full text