Religions
June 12, 2026
Yue Wang
This article argues that lotus and dharma wheel motifs in the Dunhuang Mogao Caves function not merely as decorative symbols but as active visual apparatuses that generate embodied religious experience through a mechanism we term “totemic mediation.” Drawing on Lévi-Strauss’s structuralist reading of totemism, Descola’s ontological framework, Gell’s theory of art as agency, Meyer’s “sensational...
Neuroimage
December 15, 2025
Qingyan Kong, Yue Wang, Min Li et al.
Flow is a deeply immersive state that supports optimal performance, yet its neural basis under conditions of real-world expertise remains poorly understood. Using functional MRI, this study investigated how long-term Chinese calligraphy expertise relates to flow in a culturally meaningful setting. Expert and novice participants performed imagined embodied handwriting of Kai-Shu and Cao-Shu,...
Journal of Affective Disorders
January 15, 2025
Qiongyao Yang, Yitan Yao, Xiaoping Yuan et al.
3 citations
Subanesthetic ketamine is a rapidly acting antidepressant, yet the effects of ketamine on cognitive function are inconsistent. The primary objective of this study was to explore the effects of esketamine on memory function and plasma levels of nerve growth factor (NGF) in patients with depression. A total of 132 patients with depression completed six intravenous esketamine infusions (0.4 mg/kg)...
Neuron
October 9, 2024
Luyu Fan, Youwen Zhuang, Hongyu Wu et al.
6 citations
Understanding the kinetics of LSD in receptors and subsequent induced signaling is crucial for comprehending both the psychoactive and therapeutic effects of LSD. Despite extensive research on LSD's interactions with serotonin 2A and 2B receptors, its behavior on other targets, including dopamine receptors, has remained elusive. Here, we present cryo-EM structures of LSD/PF6142-bound dopamine...
European Archives of Psychiatry and Clinical Neuroscience
September 28, 2024
Yue Wang, Qiongyao Yang, Chuanchuan Chen et al.
10 citations
Anhedonia, defined as a significant loss of interest or pleasure, is one of the core symptoms of treatment- resistant depression (TRD) and is often associated with poor prognosis. This article primarily investigates the changes in anhedonia symptoms, inflammatory markers, and cortisol levels in TRD patients after low-dose esketamine treatments. A total of sixty patients with TRD were enrolled...
Frontiers in Pharmacology
February 6, 2020
Shan Li, Xiaoxiao Luo, Dongyu Hua et al.
Patients are more likely to suffer from central nervous system (CNS) complications after anesthesia and surgery. However, postoperative depression (POD) has not yet received sufficient attentions, and its pathogenesis and therapeutic strategies remain poorly understood. We here aimed to investigate whether brain derived neurotrophic factor (BDNF)-tropomyosin-related kinase B (TrkB) signaling...