Background: Patients with end-stage renal disease receiving maintenance hemodialysis experience a substantial symptom burden, and demoralization syndrome-characterized by helplessness, hopelessness, and loss of meaning-is highly prevalent and strongly associated with impaired quality of life. However, the psychological mechanisms linking symptom burden to demoralization remain poorly...
Postpartum depression (PPD) affects 10-20% of women after childbirth, with incidence reaching 30-50% in high-risk populations. Acute postoperative pain and sleep disturbance represent modifiable risk factors. This study evaluated whether a multimodal analgesic protocol combining dexmedetomidine and esketamine is associated with reduced PPD incidence in high-risk parturients undergoing cesarean...
To compare the characteristics of resting-state functional connectivity (FC) before and after repositioning therapy in patients with benign paroxysmal positional vertigo (BPPV) using functional near-infrared spectroscopy (fNIRS). Fifty BPPV patients and fifty healthy controls were enrolled. Oxygenated hemoglobin (HbO) concentration changes during resting-state were recorded using fNIRS. The...
Cerebral CortexAugust 1, 2023Feifei Zhang, Bo Liu, Yinbo Shao et al.
Aluminum (Al) is an important environmental pathogenic factor for neurodegenerative diseases, especially mild cognitive impairment (MCI). The aim of this study was to evaluate the gray matter volume of structural covariance network alterations in patients with Al-induced MCI. Male subjects who had been exposed to Al for >10 years were included in the present study. The plasma Al concentration,...
Olfactory dysfunction (OD) is a common symptom in coronavirus disease 2019 (COVID-19) patients. Moreover, many neurological manifestations have been reported in these patients, suggesting central nervous system involvement. The default mode network (DMN) is closely associated with olfactory processing. In this study, we investigated the internetwork and intranetwork connectivity of the DMN and...
BackgroundThe precuneus/posterior cingulate cortex, which has been associated with pain sensitivity, plays a pivotal role in the default mode network. However, information regarding migraine-related alterations in resting-state brain functional connectivity in the default mode network and in local regional spontaneous neuronal activity is not adequate.MethodsThis study used functional magnetic...