Pharmacological Research
November 22, 2025
Zhuo-Ning Zhang, Xin-Yu Hao, Chen Cai et al.
5 citations
This randomized, double-blind, parallel-group trial evaluated the efficacy of a single intravenous dose of esketamine (0.3mg/kg) administered at anesthesia induction in reducing postoperative depression and anxiety among patients undergoing cardiac valve surgery. A total of 142 patients from three centers were randomly assigned to receive esketamine or saline. The primary outcomes were the...
BMC Anesthesiology
July 1, 2025
Yanan Wu, Yaning Yang, Xiaomei Wang et al.
9 citations
Postoperative sleep disturbance (PSD) is a common surgical complication. In this study, we investigated the effect of intraoperative esketamine infusion on the incidence of PSD in patients who underwent laparoscopic cholecystectomy. A single-center, double-blinded, placebo-controlled randomized clinical trial was perfomed from May to August 2024 at the People's Hospital of Ningxia Hui...
Frontiers in Psychiatry
2025
Qin Wang, Guoqin Ren, Li Sun et al.
To investigate the current status of illness perception, hope levels, coping styles, and self-transcendence among gastric cancer patients undergoing chemotherapy, and to explore the chain-mediating role of hope levels and coping styles in illness perception and self-transcendence. This study is a cross-sectional study. A convenience sampling method was used to select 507 gastric cancer patients...
Frontiers in Psychiatry
2025
Qin Wang, Guoqin Ren, Li Sun et al.
To investigate the current status and determinants of self-transcendence in gastric cancer patients undergoing chemotherapy and to establish a foundation for clinical development of interventions. A convenience sampling method was employed to select 507 gastric cancer patients undergoing chemotherapy in the oncology department of a tertiary hospital in Wuxi City, Jiangsu Province, from October...
Frontiers in Psychiatry
2025
Qin Wang, Guoqin Ren, Li Sun et al.
correction
[This corrects the article DOI: 10.3389/fpsyt.2025.1641453.].
Frontiers in Behavioral Neuroscience
October 9, 2018
Yu Yang, Weina Ju, Haining Zhang et al.
80 citations
Depression is a common mental disorder that is associated with memory dysfunction. Ketamine has recently been demonstrated to be a rapid antidepressant. The mechanisms underlying how depression induces memory dysfunction and how ketamine relieves depressive symptoms remain poorly understood. In this work, we have three groups of male C57BL/6J mice: mice exposed to chronic social defeat stress...
Li Sun
Abstract The increasing use of digital technologies in daily life has led to a growing number of studies in the field of digital psychology. While research in this area has provided valuable insights into the potential benefits and drawbacks of digital technologies for mental health and well-being, there is still much to be learned about the complex relationship between technology and...