Brain Communications
2026
Ying Wang, Chenglong Cao, Hao Chen et al.
Microvascular decompression is the standard surgical intervention for classical trigeminal neuralgia attributed to NVC. However, up to 30% of patients experience poor outcomes despite technically successful surgery, suggesting non-peripheral mechanisms. This study investigates whether central neural reorganization-manifested as altered cortico-subcortical connectivity and white matter...
Pharmacological Research
November 22, 2025
Zhuo-Ning Zhang, Xin-Yu Hao, Chen Cai et al.
5 citations
This randomized, double-blind, parallel-group trial evaluated the efficacy of a single intravenous dose of esketamine (0.3mg/kg) administered at anesthesia induction in reducing postoperative depression and anxiety among patients undergoing cardiac valve surgery. A total of 142 patients from three centers were randomly assigned to receive esketamine or saline. The primary outcomes were the...
Journal of Psychosocial Nursing and Mental Health Services
May 14, 2025
Jiaoling Du, Rumei Sha, Ying Wang
2 citations
The current meta-analysis sought to evaluate the effectiveness of mindfulness-based training (MBT) in alleviating stress and burnout among nurses, providing critical insights for their support and management in clinical environments. A literature review was conducted from April 15 to June 20, 2024, across various databases. Inclusion criteria were randomized controlled trials (RCTs) that...
Frontiers in Psychiatry
2025
Congyi Li, Zhihui Wang, Xinman Ye et al.
Clinical and preclinical studies increasingly support the antidepressant potential of several anesthetic agents, including ketamine, propofol, nitrous oxide (N2O), sevoflurane, and isoflurane. Their therapeutic effects appear to arise from the regulation of multiple interconnected systems: modulation of glutamatergic and GABAergic signaling, interaction with monoaminergic neurotransmitters...
Annals of the New York Academy of Sciences
March 1, 2024
Ruichen Hu, Shuo Li, Peijun Yuan et al.
1 citation
The relationship between integration and awareness is central to contemporary theories and research on consciousness. Here, we investigated whether and how information integration over time, by incorporating the underlying regularities, contributes to our awareness of the dynamic world. Using binocular rivalry, we demonstrated that structured visual streams, constituted by shape, motion, or...
Frontiers in Pharmacology
2024
Ruixue Liu, Chunxiao Liu, Dianwei Feng et al.
5 citations
Esketamine nasal spray (ESK-NS) is a new drug for treatment-resistant depression, and we aimed to detect and characterize the adverse events (AEs) of ESK-NS using the Food and Drug Administration (FDA) adverse event reporting system (FAERS) database between 2019 Q1 and 2023 Q4. Reporting odds ratio (ROR), proportional reporting ratio (PRR), and multi-item gamma Poisson shrinker (MGPS) were...