Psychopathology
June 15, 2026
Ary Gadelha, Bernardo Haguiara, Pedro Gabriel Lorencetti et al.
Contemporary psychiatry has advanced by decomposing behavior into discrete constructs, improving reliability but fragmenting conceptual foundations. Excessive comorbidity, blurred diagnostic boundaries, and the reification of operational criteria have created a gap between empirical data and the understanding of mental life as a coherent, lived whole - the modern paradox of "more data, less...
Schizophrenia Research
September 1, 2024
Ana Teresa Caliman-Fontes, Flávia Vieira, Gustavo C. Leal et al.
7 citations
Catatonia, documented since the 19th century, remains a significant challenge in terms of recognition and treatment. Over the last two decades, ketamine has brought new perspectives to psychiatry, sparking widespread interest. Concurrently, catatonia has attracted heightened scientific attention. Preliminary evidence suggests the therapeutic potential of ketamine for catatonia. We...
Psychiatry and Clinical Neurosciences
April 18, 2023
Lucy Chester, Lucia Valmaggia, Matthew J. Kempton et al.
Evidence for case–control studies suggests that cannabis use is a risk factor for the development of psychosis. However, there have been limited prospective studies and the direction of this association remains controversial. The primary aim of the present study was to examine the association between cannabis use and the incidence of psychotic disorders in people at clinical high risk of...
Schizophrenia Research: Cognition
December 11, 2018
Luccas Coutinho, Hianna Honorato, Cinthia Hiroko Higuchi et al.
8 citations
INTRODUCTION: Cannabis use increases the risk of developing psychosis, and subjects with psychosis are more likely to use cannabis. However, studies on the influence of cannabis on psychotic dimensions, response to treatment, and functional outcomes showed conflicting results. Such heterogeneity may be due the inclusion of patients who were already under treatment, and lack of specificity in...
Schizophrenia Bulletin
April 1, 2018
Luccas Coutinho, Cinthia H Higuchi, Daniel A. Cavalcante et al.
Abstract Background Psychotic disorders induced by cannabis may present distinct symptomatic profile, course and underlying biology. Most studies on symptomatic effects of cannabis exposure are limited by examining patients after antipsychotic treatment. We investigated if antipsychotic naive FEP patients that reported cannabis use present higher symptom’s severity and if affects deferentially...