Figshare
2025
Daniel J. Kruger, Gina Mersereau, Ashley Sullivan et al.
preprint
Abstract Background The use of psychedelics is currently increasing in the United States. Awareness of clinical trials investigating the therapeutic applications of psychedelics may result in a record number of people who use psychedelics for the first-time. This study aimed to develop a harm-reduction resource to facilitate safe and successful psychedelic experiences outside of regulated...
European Psychiatry
August 27, 2024
M. J. Gordillo Montaño, L. Rodriguez Rodriguez, C. Pérez Aparicio et al.
Introduction Kambó is considered an “ancestral medicine” by the indigenous tribes of the western region of the Amazon. Objectives Through this clinical case, the aim is to present the particularities of the symptoms and management of patients with consumption of not so common substances, such as Kambo or salvia divinorum, as well as the evolution that will occur in a patient with a previous...
European Journal of Arts Humanities and Social Sciences
May 1, 2024
Nicholas A. Kerna, Kevin D. Pruitt, N.d. Victor Carsrud et al.
Entheogens, a class of psychoactive substances with profound cultural and religious significance, have been utilized for centuries across diverse traditions for healing, spiritual exploration, and communication with the divine. Their historical usage spans continents, from the pre-Columbian Americas to traditional African practices and Ayurvedic medicine in India. While entheogens offer...
Religions
February 23, 2024
Jianyu Shen
1 citation
This article examines the earthly journey of the saints in early Jewish and Daoist hagiographies. The major texts for comparative reading are Sefer Shivchei Ha-Ar”i and Shenxian Zhuan, namely, the foundation stones of each hagiographical tradition. Emphasis is laid on the most significant phases in the process of making saints while the candidates dwell in the worldly domain as quasi-divine...
Expert Review of Clinical Pharmacology
2024
Lucas F Borkel, Jaime Rojas-Hernández, Luis Alberto Henríquez-Hernández et al.
40 citations
In psychedelic therapy, the importance of set and setting is a fundamental but under-researched assumption. The aim of this study is to correlate variables of set (psychedelic use motivation) and setting (psychedelic use location and type of companion) with psychopathology, wellbeing and personality variables. A sample of 1022 participants of the Spanish-speaking population was collected...
Journal of Islamic and Muslim Studies
November 1, 2023
Armando Montoya Jordán
Reviewed by: Mysticism and Ethics in Islam ed. by Bilal Orfali, Atif Khalil, and Mohammed Rustom Armando Montoya Jordán (bio) Mysticism and Ethics in Islam Eds. Bilal Orfali, Atif Khalil, and Mohammed Rustom Beirut: American University of Beirut Press, 2022. 476 Pages. Is the science of ethics entirely separate from mysticism, or might mysticism be the foundation of ethics? Or, conversely,...
Australian Journal of Chemistry
July 4, 2023
Scott R. Walker, Glenn A. Pullella, Matthew Piggott et al.
5 citations
The science of psychedelics is an intriguing, multi-disciplinary field that has recently been the subject of heightened public interest. This has mainly resulted from publicity associated with a number of high-profile investigations into psychedelic-assisted therapy for a range of difficult-to-treat mental health conditions. With many psychedelic substances known, including natural,...
Conatus
June 30, 2023
Željko Kaluđerović
3 citations
The paper analyses fragmentarily preserved views of Empedocles, that, in the author’s opinion, represent the antecedents of deviations from the anthropocentric vision of the world and anticipate the majority of later attempts at scientific, philosophical, and legal modifications of the status of all living beings. Empedocles, namely, claims that all beings think, i.e., that they have...
Hyperrhiz
June 12, 2023
Aaron Oldenburg
In this essay, the author details their own original experiments with using the qualities of psychedelic experiences, specifically those brought on by the atypical psychedelic, salvia divinorum, to inform game design. It discusses the brief history of games designed with varying levels of influence from psychedelic drugs and culture. It details the benefits of this approach, such as the...
Nature
May 1, 2023
Jianming Han, Jingying Zhang, Antonina L. Nazarova et al.
79 citations
The κ-opioid receptor (KOR) represents a highly desirable therapeutic target for treating not only pain but also addiction and affective disorders1. However, the development of KOR analgesics has been hindered by the associated hallucinogenic side effects2. The initiation of KOR signalling requires the Gi/o-family proteins including the conventional (Gi1, Gi2, Gi3, GoA and GoB) and...