ISSN 0004-9425
7 papers in the library · 37 citations · publishing 1970-2024
Australian Journal of Chemistry January 19, 2024 Scott R. Walker, Glenn A. Pullella, Matthew Piggott et al. correction
© 2024 The Author(s) (or their employer(s)). Published by CSIRO Publishing. This is an open access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND)
Australian Journal of Chemistry July 17, 2023 Daniel G. Anstis, Jessica Liyu, Emma K. Davison et al. 8 citations
Entheogenic natural products (e.g., psylocybin and dimethyltryptamine) are emerging as effective therapeutics to treat debilitating mood disorders that are unresponsive to conventional treatment. The detailed evaluation of psychotropic plants will conceivably lead to the discovery of structurally distinct entheogens that may offer improved or complementary medicinal properties to the classic...
Australian Journal of Chemistry July 17, 2023 Richard A Glennon, Małgorzata Dukat
Quipazine, first identified in the 1960s, has been the topic of >1000 published papers. On the basis of available 5-HT2 serotonin receptor radioligand binding data and various preclinical studies, it might be thought that quipazine bears the hallmarks of a classical hallucinogen or psychedelic agent – agents currently being examined for their potential use in treating certain neuropsychiatric...
Australian Journal of Chemistry July 11, 2023 Katie D. Lewis, Glenn A. Pullella, Han Chern Loh et al. 2 citations
Homochiral (R)- and (S)-3,4-methylenedioxymethamphetamine (MDMA) were prepared in six steps (each) from the chiral pool precursors d- and l-alanine, respectively. The key step, copper-catalysed regioselective ring-opening of an N-tosylaziridine with an aryl Grignard reagent, proceeded in high yield with complete regioselectivity. Elaboration was achieved with preservation of configurational...
Australian Journal of Chemistry July 4, 2023 Scott R. Walker, Glenn A. Pullella, Matthew Piggott et al. 5 citations
The science of psychedelics is an intriguing, multi-disciplinary field that has recently been the subject of heightened public interest. This has mainly resulted from publicity associated with a number of high-profile investigations into psychedelic-assisted therapy for a range of difficult-to-treat mental health conditions. With many psychedelic substances known, including natural,...
Australian Journal of Chemistry May 16, 2023 Eliza Milliken, Peter Galettis, Jenny Martin 4 citations
Classic psychedelics such as psilocybin, ketamine and lysergic acid diethylamide (LSD) are 5HT2A serotonin receptor agonists that produce individualised subjective affects. Today, public interest in psychedelic medicine has reached a fervour but the evidence for clinical benefit still lags. Psilocybin and psilocin are tryptophan based alkaloids found worldwide in mushrooms of the genera...
Australian Journal of Chemistry April 1, 1970 J. Picker, R. W. Rickards 18 citations
The psychotomimetic agents psilocybinl~2 (1)O\p/ OH and its dephosphorylated derivative psilooin273 were 0, ' '0-first isolated214 from the hallucinogenic Mexican + mushroom Psilocybe mexicanu Heim.The presence C H C H H e 2 of psilocybin, sometimes accompanied by psilooin, \ has subsequently been demonstrated in a number of 2 (1)species of the genus Psilocybe from Mexico,2J*6 North America,7-9...