There has been an emergence in psychedelic science in recent years, in both basic and applied research. Clinical trials have shown psychedelic drugs to be exceptionally effective in treating psychiatric illnesses such as post-traumatic stress disorder (PTSD) and depression, while other research suggests they may be effective in treating a range of other indications in the future. Outside of the...
The acute subjective effects of psychedelics are responsive to users’ expectations and surroundings (i.e., “set and setting”). Accordingly, a great deal of thought has gone into designing the psychosocial context of psychedelic administration in clinical settings. But what theoretical paradigms inform these considerations about set and setting? Here, we describe several historical, sociological...