Psychedelic-assisted therapies have demonstrated promising results in treating mental disorders, with results suggesting that the subjective intensity and quality of psychedelic experiences plays a significant role in mediating therapeutic effects. However, the strength of this association across diagnoses and treatment settings remains underexplored. We searched MEDLINE, Embase, and PsycINFO...
Depression affects over 185 million people worldwide, with approximately one-third classified as treatment-resistant depression (TRD). Current treatments, such as oral antidepressants, often take around 3 weeks to become effective, with no immediate anti-suicidal benefits. The field urgently needs innovative therapies that provide rapid relief. Psychedelics like psilocybin and ayahuasca have...
The serotonergic psychedelic N,N-dimethyltryptamine (DMT) presumably stimulates neuroplasticity in vitro and in vivo, by which it may exert neuroprotective effects during acute ischemic stroke. Since neuroplasticity has been implicated in the mechanism of action of rehabilitative therapy in stroke recovery, a pharmacological augmentation strategy facilitating neuroplasticity could be...
The purpose of the study was to describe the benefits and harm of using psychedelics in the treatment of patients with mental health and substance abuse disorders. The study focused on classic psychedelics, specifically psilocybin and LSD. The study was carried out as an integrative literature review and the data was sought using Medic, Cinahl, PubMed MEDLINE and PsycINFO databases. A total of...
This chapter explores the profound effects that non-ordinary states, particularly those induced by psychedelics, have on the brain. It highlights how psychedelics influence neural pathways, rerouting them to foster personal growth and address conditions like addiction and depression. Key mechanisms, such as the suppression of the default mode network (DMN), increased brain connectivity, and...
This chapter provides a comprehensive guide to integrating and grounding after a psychedelic journey. Grounding is essential for solidifying the insights gained from a non-ordinary state of consciousness (NOSC) and ensuring they contribute to lasting healing and transformation. The chapter emphasizes the importance of rebuilding your aura and energetic field, which can become vulnerable after...
This chapter explores the intricate connections between transpersonal psychology, psychedelic experiences, and the power of art as a therapeutic tool. It delves into how altered states of consciousness—achieved through psychedelics or techniques like meditation and breathwork—allow individuals to access deeper realms of the psyche, facilitating spiritual and psychological growth. The work of...
Introduction Considering the increasing evidence supporting psilocybin’s efficacy in therapeutic settings, it is essential to deepen our understanding of its subjective meanings and effects to enhance its integration into psychotherapy. Current knowledge is primarily based on psychometric assessments or unstructured personal reports, leaving a gap in the qualitative analysis of subjective...
Innovations in the field of positive psychology are rare nowadays, so new research approaches are needed to develop the field further. In the article, the incorporation of therapy effectiveness factors into positive psychology interventions is suggested. Furthermore, it examines the benefits and limitations of the integration of cognitive behavioral therapy methods, psychedelics, breathing...
Objective: Prior research has found an association between psychedelic use and reduced stigma attached to mental illness. However, whether psychedelics alleviate stigma-related distress remains unclear. Since stigma impacts different groups uniquely, any moderating effect of psychedelics on stigma-related distress is likely to vary across subpopulations. This study addresses two main questions:...