Journal of Addiction Medicine
May 28, 2025
Sara Prostko, Alexander Wu, Samuel Maddams et al.
2 citations
Psychedelics may be promising treatments for substance use disorders (SUD). This study aims to understand how individuals with alcohol use disorder (AUD), opioid use disorder (OUD), and psychiatric disorders perceive and experience psychedelics for both nonmedical and medical use. Data for this cross-sectional survey study were collected from June 2023 to February 2024 at a large, tertiary...
Journal of Psychopharmacology
May 26, 2025
Kyle Patch, William R. Smith
3 citations
Research on the therapeutic potential of psychedelics has surged, prompting a re-examination of the role of set and setting in psychedelic-assisted therapy. Yet, these concepts are vague and typically defined over inclusively. We believe that set and setting research should be methodologically reductionist, focusing on specific components rather than set and setting as such. To that end, we...
Journal of Eating Disorders
May 26, 2025
Julie Trim, Samantha Shao, Nadav Liam Modlin et al.
14 citations
PT may hold promise not only in the treatment of eating disorders but also trauma-related disorders, including PTSD and dissociative amnesia. Potential mechanisms of psilocybin's facilitation of remembering and processing traumatic material is reviewed.
The International Journal of Neuropsychopharmacology
May 25, 2025
Ines Erkizia-Santamaría, Nerea Martínez-Álvarez, Leyre Salinas-Novoa et al.
7 citations
Abstract Background The psychedelic psilocybin has been posited as efficacious for the treatment of depression. However, the potential link between the intensity of acute psychedelic effects and long-term therapeutic outcomes remains undiscovered. Moreover, the impact of classical antidepressant drugs that modulate serotonergic activity on psilocybin’s effects is a clinically relevant concern....
Medical & Clinical Case Reports Journal
May 19, 2025
Andrés David Turizo Smith, Natalia Jaramillo, Diana Milena Berrío Cuartas
Psilocybin, a psychedelic compound in certain mushrooms, has been used for centuries in spiritual ceremonies and neuropsychiatric therapy.Despite its stigmatization as a Schedule I substance in 1970, research into psilocybin has resurged since the early 2000s, particularly in psychiatry and palliative care.This review examines psilocybins potential to improve the quality of life in palliative...
Journal of Psychedelic Studies
May 16, 2025
Oskar Enghoff, Margit Anne Petersen, Søren Holm et al.
Abstract Background and aims Online platforms are popular for exchanging information about psychedelics, including consumption advice. The recent resurgence of public interest in psychedelics will likely intensify this. We aim to further the understanding among researchers, policy makers, medical practitioners, harm reduction practitioners, and social workers, of contemporary psychedelic...
May 16, 2025
Lukas A Basedow, Lynn Lottes, Irina Falkenberg et al.
1 citation
preprint
Background: Despite significant advancements in the treatment of depression, challenges such as inadequate response rates and high placebo effects highlight the need for improved therapies and a deeper understanding of treatment expectations. Patient expectations play a crucial role in treatment outcomes but have not been systematically investigated in the context of novel interventions like...
Journal of Psychedelic Studies
May 16, 2025
Anna-Leigh Hodge, Anna Forsyth, Tehseen Noorani et al.
6 citations
Abstract Psilocybin, a naturally occurring psychedelic compound found in certain fungi has long been used by Indigenous cultures within ritual and ceremony for healing and spiritual purposes (Spiers et al., 2024). While emerging evidence points to psychedelic agents being novel avenues for the treatment of substance use disorders, the predominantly Western medical models of psychedelic-assisted...
Journal of Psychedelic Studies
May 15, 2025
Terence H. W. Ching, Benjamin Kelmendi
4 citations
AbstractBackgroundThere is a need to systemically diversify psychedelic clinical trials, considering the growing interest in in the therapeutic potential of psychedelics within Black, Indigenous, and Peoples of Color (BIPOC) and queer communities. Doing so contributes to a more inclusive foundation of evidence-based research and addresses ethical considerations surrounding anticipated demand...
ACS Pharmacology & Translational Science
May 15, 2025
Haojiang Zhai, Hongshuang Wang, Haohong Li et al.
3 citations
The interplay between psychedelics, such as psilocybin, lysergic acid diethylamide (LSD) and dimethyltryptamine (DMT), and sleep is an emerging area, but their impact on sleep remains relatively underexplored. This viewpoint provides a perspective on how psychedelics may alter sleep phases, dreaming, and their potential therapeutic applications for sleep disorders.