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Psilocybin: all studies

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Research

PSILOCYBIN STUDIES TURN A NEW LEAF

Chemical & Engineering News July 17, 2006 Ivan Amato

RETURN TO ISSUEPREVNewsNEXTPSILOCYBIN STUDIES TURN A NEW LEAFScientists aim to set psychedelics research on a sound scientific footingIVAN AMATOCite this: Chem. Eng. News 2006, 84, 29, 10Publication Date (Print):July 17, 2006Publication History Published online14 November 2010Published inissue 17 July...

DOI: 10.1021/cen-v084n029.p010a (opens in new tab) Psilocybin Turn biochemistry Nanotechnology Hallucinogen

Psilocybin can occasion mystical-type experiences having substantial and sustained personal meaning and spiritual significance

Psychopharmacology July 7, 2006 Roland R. Griffiths, William A. Richards, U. Mccann et al. 1,684 citations

RationaleAlthough psilocybin has been used for centuries for religious purposes, little is known scientifically about its acute and persisting effects.ObjectivesThis double-blind study evaluated the acute and longer-term psychological effects of a high dose of psilocybin relative to a comparison compound administered under comfortable, supportive conditions.Materials and methodsThe participants...

DOI: 10.1007/s00213-006-0457-5 (opens in new tab) Psilocybin Anxiety Hallucinogen Clinical psychology +1

Response of cluster headache to psilocybin and LSD

Neurology June 26, 2006 R. Andrew Sewell, John H. Halpern, Harrison G. Pope 259 citations

The authors interviewed 53 cluster headache patients who had used psilocybin or lysergic acid diethylamide (LSD) to treat their condition. Twenty-two of 26 psilocybin users reported that psilocybin aborted attacks; 25 of 48 psilocybin users and 7 of 8 LSD users reported cluster period termination; 18 of 19 psilocybin users and 4 of 5 LSD users reported remission period extension. Research on...

DOI: 10.1212/01.wnl.0000219761.05466.43 (opens in new tab) Ipilimumab Nivolumab Demographics Adverse effect +4

Effects of psilocybin on time perception and temporal control of behaviour in humans

Journal of Psychopharmacology May 20, 2006 Marc Wittmann, Olivia Carter, Felix Hasler et al. 245 citations

Hallucinogenic psilocybin is known to alter the subjective experience of time. However, there is no study that systematically investigated objective measures of time perception under psilocybin. Therefore, we studied dose-dependent effects of the serotonin (5-HT) 2A/1A receptor agonist psilocybin (4-phosphoryloxy-N, N-dimethyltryptamine) on temporal processing, employing tasks of temporal...

DOI: 10.1177/0269881106065859 (opens in new tab) Psilocybin Time perception Cognition Hallucinogen +4

Investigation into the temporal stability of aqueous standard solutions of psilocin and psilocybin using high performance liquid chromatography

Science & Justice April 1, 2006 Nicole Anastos, Neil W. Barnett, Frederick M. Pfeffer et al. 27 citations

This paper reports an investigation into the temporal stability of aqueous solutions of psilocin and psilocybin reference drug standards over a period of fourteen days. This study was performed using high performance liquid chromatography utilising a (95:5% v/v) methanol: 10 mM ammonium formate, pH 3.5 mobile phase and absorption detection at 269 nm. It was found that the exclusion of light...

DOI: 10.1016/s1355-0306(06)71579-9 (opens in new tab) Psilocybin Chromatography Ingredient Hallucinogen +1

Aeruginascin, a Trimethylammonium Analogue of Psilocybin from the Hallucinogenic MushroomInocybe aeruginascens

Planta Medica April 1, 2006 Niels Jensen, Jochen Gartz, Hartmut Laatsch 56 citations

The hallucinogenic mushroom Inocybe aeruginascens contains several typical Psilocybe alkaloids including psilocybin. We have now elucidated the structure of a further indole derivative named aeruginascin as the quaternary ammonium compound N, N, N-trimethyl-4-phosphoryloxytryptamine. Aeruginascin is closely related to the frog skin toxin bufotenidine (5-HTQ), a potent 5-HT3 receptor agonist,...

DOI: 10.1055/s-2006-931576 (opens in new tab) Psilocybin Hallucinogen Stereochemistry Agonist +5

The Determination of Psilocin and Psilocybin in Hallucinogenic Mushrooms by HPLC Utilizing a Dual Reagent Acidic Potassium Permanganate and Tris(2,2′‐bipyridyl)ruthenium(II) Chemiluminescence Detection System

Journal of Forensic Sciences 2006 Nicole Anastos, Simon W. Lewis, Neil W. Barnett et al. 44 citations

ABSTRACT: This paper describes a procedure for the determination of psilocin and psilocybin in mushroom extracts using high‐performance liquid chromatography with postcolumn chemiluminescence detection. A number of extraction methods for psilocin and psilocybin in hallucinogenic mushrooms were investigated, with a simple methanolic extraction being found to be most effective. Psilocin and...

DOI: 10.1111/j.1556-4029.2005.00033.x (opens in new tab) Psilocybin Potassium permanganate Chromatography Chemiluminescence +5