ISSN 1526-632X
33 papers in the library · 1,533 citations · publishing 1955-2026
Neurology June 9, 2026 Emmanuelle A. D. Schindler, Kevin Lenaburg, Robert Wold
To carry out a survey on N,N-dimethyltryptamine (DMT) use in adults with cluster headache.
Neurology November 1, 2025 Martin A. Samuels
Abstract This chapter presents a case of a man in his 70s who, despite being generally healthy, enters a dissociative state triggered by a fraudulent computer message and a commanding voice. He follows instructions to withdraw $27,000 and deposit it in a Bitcoin machine, while his wife observes his trance-like compliance despite her protests. The chapter explores dissociation as a...
Neurology May 16, 2025 Sneha Mantri
Her earrings tremble as she tilts her head.Voice cracking, he mimes the difficulty of spooning soup up to his mouth.The MRI's pixels reflect off his glasses, obscuring the worry in his eyes.
Neurology April 7, 2025 Emmanuelle A. D. Schindler, Christopher Gottschalk, Deepak Cyril D’souza 2 citations
To examine the relationship of acute psychedelic effects and measures of mental health with headache frequency in clinical trials of psilocybin in migraine and cluster headache.
Neurology March 30, 2025 Julian Ungar-Sargon
This article examines the question of whether living beings possess an innate, unchangeable nature or have the capacity for fundamental transformation a question with profound implications for treating addiction-related physical illness. By integrating diverse perspectives from religious and philosophical traditions, mystical thought, modern neuroscience, genetics, and clinical approaches to...
Neurology February 25, 2025 David Fischer, Brian L Edlow, Holly J Freeman et al. 9 citations
Determining the level of consciousness in patients with brain injury-and more fundamentally, establishing what they can experience-is ethically and clinically impactful. Patient behaviors may unreliably reflect their level of consciousness: a subset of unresponsive patients demonstrate covert consciousness by willfully modulating their brain activity to commands through fMRI or EEG. However,...
Neurology April 9, 2024 Tina Singh, Dipa Patel, Kasey Bishop et al. 1 citation
To uncover the underlying mechanisms between the usage of psilocybin and its impact on the rehabilitation from substance use disorders (SUD).
Neurology September 19, 2018 K. Fox, Jennifer Yih, Omri Raccah et al.
Objective We applied direct cortical stimulation (DCS) to the orbitofrontal cortex (OFC) in neurosurgical patients implanted with intracranial electrodes to probe, with high anatomic precision, the causal link between the OFC and human subjective experience. Methods We administered 272 instances of DCS at 172 OFC sites in 22 patients with intractable focal epilepsy (from 2011 to 2017), none of...
Neurology September 5, 2018 L. Weizman, Lior Dayan, Silviu Brill et al.
Objective To characterize the functional brain changes involved in δ-9-tetrahydrocannabinol (THC) modulation of chronic neuropathic pain. Methods Fifteen patients with chronic radicular neuropathic pain participated in a randomized, double-blind, placebo-controlled trial employing a counterbalanced, within-subjects design. Pain assessments and functional resting state brain scans were performed...
Neurology April 18, 2017 D. Wheelwright, N. Dangayach, Stephen Griffiths et al.
Objective: We hypothesize that intra-ICU initiation of guided mindfulness meditation is feasible and will help prevent the development of anxiety and depression in good grade SAH patients. Background: Aneurysmal Subarachnoid Hemorrhage (SAH) has a case fatality rate of about 20%. Of all SAH patients, 40% are “good grade” defined as Hunt-Hess 1–2 with normal mental status whereas 60% are poor...
Neurology September 29, 2015 Venus Tang, Wai S Poon, Patrick Kwan
To investigate the effectiveness of mindfulness-based therapy (MT) and social support (SS) in patients with drug-resistant epilepsy. We performed an assessor-blinded randomized control trial. Sixty patients with drug-resistant epilepsy were randomly allocated to MT or SS (30 per group). Each group received 4 biweekly intervention sessions. The primary outcome was the change in the total score...
Neurology May 1, 2015 Francisco de Assis Aquino Gondim, Sarah H Griesbach, Florian P Thomas
Objective: To discuss the neuropsychiatric phenomena described in Cantigas de Santa Maria (Canticles of St. Mary [CSM]). Background: CSM is a collection of 427 canticles composed in Galician-Portuguese between 1252 and 1284 at the Court of King Alfonso X the Wise of Spain (1221-1284). The canticles (of which 9 are repeated) include devotional and liturgical poems and 353 narrative stories...
Neurology April 6, 2015 Thananan Thammongkolchai, Pichet Termsarasab, Ayham Alkhachroum et al. 43 citations
Objective: To report the first case of myoclonus as neurologic presentation of 5-MeO-DALT abuse Background: 5-Meo-DALT (N,N-diallyl-5-methoxytryptamine) is a relatively new hallucinogen, initially sold online in 2004. It is a psychedelic compound from the tryptamine family which affects monoamine neurotransmitters including dopamine and serotonin. It is a psychostimulant with strong visual...
Neurology April 6, 2015 Sarah Dolgonos, Kamil Detyniecki
OBJECTIVE: To evaluate feasibility of and receptivity for stress-management training during neurology residency BACKGROUND: Exhaustion, sleep deprivation, and stress are widespread among residents. Studies have shown that physicians who undertake mindfulness training report decreased anger, fatigue, and depression, and an increased sense of personal accomplishment. Standardized mindfulness...
Neurology April 6, 2015 Jeffrey Kornitzer, Michelle Philips, David F. Marks et al.
OBJECTIVE: In this case report, we relate a unique case of Alice in Wonderland Syndrome in a woman with a right temporo-parietal cavernoma. BACKGROUND: Alice in Wonderland Syndrome (AIWS) is a rare constellation of perceptual disturbances marked by distorted body image and metamorphopsia_ illusory changes in the form, size, distance, or color of stationary objects. Although the cause of AIWS is...
Neurology April 6, 2015 Sara Razmjou, Darcy Litteljohn, Shawn P. Hayley
Objective: To evaluate the potential synergistic effect of ketmaine and magnesium treatment on prefrontal cortex (PFC) and hippocampal BDNF expression and depressive-like behavior in mice model. Background: Ketamine, an NMDA receptor antagonist with neuroplastic effect on up-regulation of BDNF, has been investigated significantly as a fast acting antidepressant particularly in treatment...
Neurology April 8, 2014 Yoshie Umemura, Thomas A. Andrew, Valerie L. Jacobs et al.
OBJECTIVE: To describe a fatal outcome due to ingestion of a new designer drug, 25I-NBOMe. BACKGROUND: Abuse of synthetic drugs has been on the rise, and many are sold over-the-counter as bath salts and fertilizer. Identification of the exposure to such chemicals is often difficult due to the paucity of available specific laboratory assays. 25I-NBOMe stands for...
Neurology September 3, 2013
The increasing prevalence of allergic airway diseases in industrialized countries has been associated with high hygienic standards and reduced microbial exposure. Probiotic lactic acid bacteria, such as certain Lactobacillus strains, were shown to have potentially beneficial immunomodulatory properties. Therefore, we determined the effect of intranasal administration of L. rhamnosus GG (LGG)...
Neurology February 12, 2013 R. Wells, Gloria Y Yeh, C. Kerr et al.
OBJECTIVE: Our objective was to determine whether Mindfulness Based Stress Reduction (MBSR) would improve functional connectivity of the DMN and reduce hippocampal atrophy among adults with Mild Cognitive Impairment (MCI).
Neurology July 4, 2011 Una D. Mccann, Francis P. Sgambati, Alan R. Schwartz et al. 1 citation
Background: Methylenedioxymethamphetamine (MDMA, "ecstasy") is a popular recreational drug of abuse and a selective brain serotonin neurotoxin.Functional consequences of MDMA neurotoxicity have defied ready characterization.Obstructive sleep apnea (OSA) is a common form of sleep-disordered breathing in which brain serotonin dysfunction may play a role.The present study sought to determine...
Neurology January 13, 2011 Jeffrey R. Petrella, Forrest Sheldon, Steven E. Prince et al. 291 citations
OBJECTIVE: Dysfunction of the default mode network (DMN) has been identified in prior cross-sectional fMRI studies of Alzheimer disease (AD) and mild cognitive impairment (MCI); however, no studies have examined its utility in predicting future cognitive decline. METHODS: fMRI scans during a face-name memory task were acquired from a cohort of 68 subjects (25 normal control, 31 MCI, and 12 AD)....
Neurology September 1, 2010
MS quality of life, depression, and fatigue improve after mindfulness training: a randomized trial.
Neurology January 26, 2010 S Silva, X Alacoque, O Fourcade et al.
The ascending reticular activating system (ARAS) modulates circadian wakefulness, which is preserved in a persistent vegetative state (PVS). Its metabolism is preserved. Impairment of metabolism in the polymodal associative cortices (i.e., precuneus) is characteristic of PVS where awareness is abolished. Because the interaction of these 2 structures allows conscious sensory perception, our...
Neurology March 5, 2007 Kevin R. Nelson, Michelle Mattingly, Frederick A. Schmitt 60 citations
In a study of more than 13,000 Europeans, 5.8% reported the out-of-body experience (OBE) form of autoscopy.1 Occurring in diverse clinical settings, OBE is also typical of near death experience (NDE). NDE are responses to life-threatening crisis characterized by a combination of dissociation from the physical body, euphoria, and transcendental or mystical elements. Persons with NDE may have an...
Neurology June 26, 2006 R. Andrew Sewell, John H. Halpern, Harrison G. Pope 259 citations
The authors interviewed 53 cluster headache patients who had used psilocybin or lysergic acid diethylamide (LSD) to treat their condition. Twenty-two of 26 psilocybin users reported that psilocybin aborted attacks; 25 of 48 psilocybin users and 7 of 8 LSD users reported cluster period termination; 18 of 19 psilocybin users and 4 of 5 LSD users reported remission period extension. Research on...