Lila Harris, Zachary Smith, Richard J. Ortiz et al.
preprint
Abstract Background: LSD is a hallucinogen with complex neurobiological and behavioral effects. Underlying these effects are changes in brain neuroplasticity. This is the first study to follow the developmental changes in brain structure and function following LSD exposure in periadolescence. Methods: Female and male mice were given vehicle, single or multiple treatments of 3.3 µg of LSD by...
Ngo Cheung
preprint
Cognitive impairment—rather than psychosis or mood instability—often drives long-term disability in schizoaffective disorder, yet current antipsychotic and mood-stabilising regimens offer little relief. We describe a 22-year-old man with schizoaffective disorder, bipolar type, whose persistent "brain fog" jeopardised university graduation despite euthymic mood and quiescent psychosis on...
Cristina Martinez Montes, Birgit Penzenstadler
preprint
Abstract Context: Individual sustainability is undermined by continuous stress, a circumstance many software developers and computer workers are constantly exposed to via deadlines, over-commitment, and high workload. Purpose: We analyze the experience of IT workers when using a deep breathing practice to improve wellbeing, considering their perception of impacts in both benefits and...
Nakul Kumar
BACKGROUND Organic chemistry and biological applications of the newly synthesized organic molecules OBJECTIVE To identify the effects of neurotransmitter and the effects of chemical imbalance in human brain METHODS Literature study, Experimental and analysis RESULTS The effects of the chemical imbalance are highly responsible for many neurotransmitter disease. CONCLUSIONS In conclusion,...
Brandon L Alderman, Ryan L Olson, C.J. Brush et al.
Mental and physical (MAP) training is a novel clinical intervention that combines mental training through meditation and physical training through aerobic exercise. The intervention was translated from neuroscientific studies indicating that MAP training increases neurogenesis in the adult brain. Each session consisted of 30 min of focused-attention (FA) meditation and 30 min of...
Elizaveta Solomonova, Simon Dubé, Cloé Blanchette-Carrière et al.
Study objectives: Rapid eye movement (REM) sleep, non-rapid eye movement (NREM) sleep, and sleep spindles are all implicated in the consolidation of procedural memories. The relative contributions of sleep stages and sleep spindles was previously shown to depend on individual differences in task processing. Experience with Vipassana meditation is one such individual difference that has not been...
Julia C. Basso, Sarah Lynn
BACKGROUND Mindfulness and meditation have a rich historical tradition, and a growing scientific base of evidence supports their use in creating positive psychological and neuroplastic changes for practitioners. Though meditation can be taught in various ways, the scientific community has yet to systematically study different types of meditation on neuropsychological outcomes, especially as it...
H. Aung, S. Yati
Background: Schizophrenia, characterized by symptoms such as auditory and visual hallucinations, imposes significant challenges on mental health care. Recent research highlights the potential of meditation to alleviate symptoms by enhancing emotional regulation and neuroplasticity. This study examines the role of meditation as an adjunctive therapy for schizophrenia, exploring its...
Amanda Timek, Catherine Daniels-Brady, Stephen Ferrando
preprint
Abstract Background : Anorexia nervosa is a life-threatening psychiatric illness with a high mortality rate and limited treatment options. This illness is frequently comorbid with major depressive disorder, leading to additional obstaces in patient quality of life, and increasing the mortality rate further due to risk of suicide. Ketamine, an competitive N-methyl-D-aspartate receptor...
Research Square
Jack Swain, Davis Carter, Leonardo Vando et al.
preprint
Abstract Background Sleep disturbances are a significant public health burden affecting 50 to 70 million adults in the United States and contributing to impaired cognition, accelerated disease progression, and increased mortality risk. 1,2 Available pharmacological treatments carry notable safety and tolerability risks, while access to the leading evidence-based behavioral intervention,...