We estimated lifetime prevalence of psychedelic use (lysergic acid diethylamide (LSD), psilocybin (magic mushrooms), mescaline, and peyote) by age category using data from a 2010 US population survey of 57,873 individuals aged 12 years and older. There were approximately 32 million lifetime psychedelic users in the US in 2010; including 17% of people aged 21 to 64 years (22% of males and 12% of...
Dissecting Serotonin Receptors Serotonin receptors are the targets for many widely used drugs prescribed to treat ailments from depression to obesity and migraine headaches (see the Perspective by Palczewski and Kiser ). C. Wang et al. (p. 610 , published online 21 March) and Wacker et al. (p. 615 , published online 21 March) describe crystal structures of two members of the serotonin family of...
Serotonergic hallucinogens such as (+)-lysergic acid diethylamide (LSD) and dimethyltryptamine (DMT) produce distinctive visual effects, whereas the synthetic hallucinogen N,N-diisopropyltryptamine (DiPT) is known for its production of auditory distortions. This study compares the discriminative stimulus effects of DiPT to those of visual hallucinogens. Adult male rats were trained to...
Distributed by Icarus Films, 32 Court St., 21st Floor, Brooklyn, NY 11201; 800-876-1710Produced by Venture Film in coproduction with RSI – Radiotelevisione svizzera, Teleclub, Lichtblick Filmproduktion, and Spotlight Media ProductionsDirected by Martin Witz2011, DVD, color and b&w, 81 min. The Substance is a social and cultural history of lysergic acid diethylamide, or LSD. LSD began as an...
European Psychiatry2013V.M. Barrau-Alonso, J. Sendra-Lopez, N. Benítez-Álvarez et al.1 citation
Introduction Psychedelic drugs were used extensively in psychotherapy in the 1950s to lower psychological defences and facilitate emotional insight. Thousands of research participants were administered hallucinogens in the context of basic clinical research or therapeutic clinical research, resulting in hundreds of publications. Results across studies were ultimately inconclusive due to such...
The word ‘psychedelic’ was coined in the 1950s by psychiatrist Humphry Osmond to describe hallucinogenic drugs like mescaline and LSD – but this essay will not be about either the history of ‘head’ films or how to write film history on acid. What I want to do is to show what film historians can learn from J.H. Hexter’s writings on the rhetoric of history, including a look at what he meant when...
The use of Synthetic Cathinones and Tryptamines in a Psychiatric Population A new wave of designer drugs is emerging in both emergency room (ER) patients and the community at large. These drugs commonly known and sold as "bath salts" produce toxic effects as well as disturbing psychopathological symptoms. These drugs are a synthetic modification of the naturally occurring alkaloid cathinone,...
Though synesthesia research has seen a huge growth in recent decades, and tremendous progress has been made in terms of understanding the mechanism and cause of synesthesia, we are still left mostly in the dark when it comes to the mechanistic commonalities (if any) among developmental, acquired and drug-induced synesthesia. We know that many forms of synesthesia involve aberrant structural or...
An increase in the consumption of vegetable substances with a hallucinogenic effect has been observed. Some of these substances are associated with ancestral religious ceremonies, while many of them are legal or are partially regulated. Salvia divinorum is a powerful kappa receptor agonist, with dissociative and hallucinogenic properties, which start quickly and have a short duration. Kratom...
Along with writers like Norman Mailer and Joan Didion, Tom Wolfe's works of the mid-1960s ushered in the age of "new journalism," a term that Wolfe (born 1930) himself coined. His celebrated bestselling novel, The Electric Kool-Aid Acid Test, broke with many of the conventions to which reporters and journalists typically adhered. Rather than simply describing from an objective standpoint the...