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LSD: all studies

Page 198 of 282: studies 1,971 to 1,980 of 2,815, newest first. Back to the LSD overview

Research

Is Therapeutic Use of Psychedelic Medication Influenced by Bias?

Journal of the American Psychiatric Nurses Association August 10, 2023 G. Pearson

The use of psychedelic medications to treat the brain disorders associated with psychiatric illness has re-emerged in recent years as a viable treatment option (Grieco et al., 2022). Historically there is evidence of hallucinogenic use in religious and spiritual rituals dating back to 500 B.C. (Begola & Dowben, 2018). The discovery of LSD (lysergic acid diethylamine-25) in Switzerland in 1943...

Substance use, harm reduction attitudes and behaviors among attendees of nature rave parties in Israel.

Harm Reduction Journal August 9, 2023 Hagit Bonny-Noach, Barak Shapira, Pinchas Baumol et al. 9 citations

Few studies have analyzed harm reduction behaviors and attitudes among rave party attendees. Since the late 1980s, there has been a large Israeli rave scene, also known as 'Nature Parties'. However, only a few studies have been conducted among nature party attendees and almost all of them are from a qualitative perspective. This study's aim was to fill the gap and conduct quantitative research...

Der Rote Keulenkopf

Chemie in Unserer Zeit August 3, 2023 Frank P. Petersen

Zusammenfassung 1935 isolierten der englische Chemiker Harold Ward Dudley und der schottische Frauenarzt John Chassar Moir das hochpotente, uterotone Ergometrin aus den Sklerotien des Roten Keulenkopfs. Forscherteams in England und den USA zeigten, dass alle damals bekannten Ergotalkaloide einen identischen Baustein besitzen, die Lysergsäure. Die neuen Erkenntnisse motivierten den Schweizer...

Structure-Activity Assessment and In-Depth Analysis of Biased Agonism in a Set of Phenylalkylamine 5-HT2A Receptor Agonists.

ACS Chemical Neuroscience August 2, 2023 Eline Pottie, Christian B M Poulie, Icaro A Simon et al. 25 citations

Serotonergic psychedelics are described to have activation of the serotonin 2A receptor (5-HT2A) as their main pharmacological action. Despite their relevance, the molecular mechanisms underlying the psychedelic effects induced by certain 5-HT2A agonists remain elusive. One of the proposed hypotheses is the occurrence of biased agonism, defined as the preferential activation of certain...

DOI: 10.1021/acschemneuro.3c00267 (opens in new tab) Full text (opens in new tab) 5-ht2a Biased agonism In vitro pharmacology Minigαq +6

SAINDO DO ESTIGMA: PSICODÉLICOS COMO ALTERNATIVA VIÁVEL NA PROMOÇÃO DA SAÚDE MENTAL

August 1, 2023 Gabriel Alexandre Moura, ANA Cecilia de Carvalho Cunha, Beatriz Barros Cordeiro et al.

Objetivo: O uso de psicodélicos em psicoterapia tem sido objeto de interesse crescente na última década.Portanto, o objetivo desta revisão sistemática é examinar a literatura científica mais recente sobre os benefícios do uso de psicodélicos na promoção da saúde mental.Metodologia: Os descritores para essa pesquisa foram selecionados pela Descritores em ciência da saúde (DeCS/MeSH), da...

Potential neonatal toxicity of new psychoactive substances.

Pharmacology & Therapeutics August 1, 2023 Ryoichi Fujiwara, Megan Journey, Fatimah Al-Doori et al. 13 citations

Cannabis, cocaine, 3,4-methylenedioxymethamphetamine, and lysergic acid diethylamide are psychoactive substances with a significant increase in consumption during the 21st century due to their popularity in medicinal and recreational use. New psychoactive substances (NPSs) mimic established psychoactive substances. NPSs are known as being natural and safe to consumers; however, they are neither...

Psychedelic medicines for end-of-life care: Pipeline clinical trial review 2022.

Palliative & Supportive Care August 1, 2023 Xuepeng Jing, Nicholas Hoeh, David B Menkes 18 citations

People with terminal illnesses often experience psychological distress and associated disability. Recent clinical trial evidence has stimulated interest in the therapeutic use of psychedelics at end of life. Much uncertainty remains, however, mainly due to methodological difficulties that beset existing trials. We conducted a scoping review of pipeline clinical trials of psychedelic treatment...

THE CONNECTION BETWEEN THE INDIVIDUAL SUBJECTIVE WELL-BEING AND THE MYSTICAL EXPERIENCE PRODUCED BY THE USE OF PSYCHEDELICS

PSYCHOLOGICAL JOURNAL July 31, 2023 Tetiana Kudrina, Kozlovska Anna

Respondents with experience in the use of psychedelics (psilocybin, LSD, ketamine, MDMA, etc.) participated in the study. Based on the subjective assessment of the level of awareness in the topic of psychedelics, it was found that 49% of respondents have a high level, 47% have an average level, and 4% have a low level of awareness in the topic. Most of the study participants were in Ukraine...

Med Check: FDA, Anti-Amyloid Beta Vaccine, Clinical Trials of Psychedelics, and Lumryz

Psychiatric News July 27, 2023 Terri D’arrigo 1 citation

Back to table of contents Previous article Next article Med CheckFull AccessMed Check: FDA, Anti-Amyloid Beta Vaccine, Clinical Trials of Psychedelics, and LumryzTerri D’ArrigoTerri D’ArrigoSearch for more papers by this authorPublished Online:27 Jul 2023https://doi.org/10.1176/appi.pn.2023.08.8.3FDA Expedites Review of Anti-Amyloid Beta Vaccine for Alzheimer’s DiseaseThe Food and Drug...

5-HT2AR and NMDAR psychedelics induce similar hyper-synchronous states in the rat cognitive-limbic cortex-basal ganglia system.

Communications Biology July 26, 2023 Ivani Brys, Sebastian A Barrientos, Jon Ezra Ward et al. 33 citations

The profound changes in perception and cognition induced by psychedelic drugs are thought to act on several levels, including increased glutamatergic activity, altered functional connectivity and an aberrant increase in high-frequency oscillations. To bridge these different levels of observation, we have here performed large-scale multi-structure recordings in freely behaving rats treated with...

DOI: 10.1038/s42003-023-05093-6 (opens in new tab) Full text (opens in new tab) Psychedelics Brain waves Consciousness Pharmacology