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Ryoichi Fujiwara

2 papers in the library · 13 citations · publishing 2018-2023

Papers

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Potential neonatal toxicity of new psychoactive substances.

Pharmacology & Therapeutics August 1, 2023 Ryoichi Fujiwara, Megan Journey, Fatimah Al-Doori et al. 13 citations

Cannabis, cocaine, 3,4-methylenedioxymethamphetamine, and lysergic acid diethylamide are psychoactive substances with a significant increase in consumption during the 21st century due to their popularity in medicinal and recreational use. New psychoactive substances (NPSs) mimic established psychoactive substances. NPSs are known as being natural and safe to consumers; however, they are neither...

Altered metabolism of synthetic cannabinoid JWH-018 by human cytochrome P450 2C9 and variants.

Biochemical and Biophysical Research Communications April 6, 2018 Amy L Patton, Kathryn A Seely, Azure L Yarbrough et al.

Synthetic cannabinoids (SCBs), synonymous with 'K2', 'Spice' or 'synthetic marijuana', are psychoactive drugs of abuse that frequently result in clinical effects and toxicity more severe than those classically associated with Δ9-tetrahydrocannabinol such as extreme agitation, hallucinations, supraventricular tachycardia, syncope, and seizures. JWH-018 is one of the earliest compounds identified...

DOI: 10.1016/j.bbrc.2018.03.028 (opens in new tab) Full text (opens in new tab) Cyp2c9 variants Cyp450 Enzyme kinetics Synthetic cannabinoids +1