Pharmacological Reports
October 24, 2023
Agnieszka Wsół
56 citations
Abstract Psychedelics are powerful psychoactive substances that alter perception and mood processes. Their effectiveness in the treatment of psychiatric diseases was known before their prohibition. An increasing number of recent studies, due to the indisputable resurgence of serotonergic hallucinogens, have shown their efficacy in alleviating depression, anxiety, substance abuse therapies, and...
Journal of Palliative Medicine
October 1, 2023
Noah D Gold, Austin J. Mallard, Jacob C Hermann et al.
5 citations
Background: Amyotrophic lateral sclerosis (ALS) is an aggressive, terminal neurodegenerative disease that causes death of motor neurons and has an average survival time of 3-4 years. ALS is the most common motor neuron degenerative disease and is increasing in prevalence. There is a pressing need for more effective ALS treatments as available pharmacotherapies do not reverse disease progression...
Berkeley Undergraduate Journal
September 7, 2023
Dylan Earp
There has been an emergence in psychedelic science in recent years, in both basic and applied research. Clinical trials have shown psychedelic drugs to be exceptionally effective in treating psychiatric illnesses such as post-traumatic stress disorder (PTSD) and depression, while other research suggests they may be effective in treating a range of other indications in the future. Outside of the...
Research Square
September 1, 2023
José Ferrer Costa, Nuria Moran, Carlos Garcia Marti et al.
2 citations
preprint
Abstract Objective The main objective was to evaluate the impact of an 8-week virtual reality (VR) based educational program teaching mindfulness and emotional management techniques to healthcare professionals. Methods Eighty-six healthcare professionals from two primary care centers and a palliative care team engaged in weekly 10-15 minute VR educational sessions. The sessions focused on...
Journal of Pain and Symptom Management
September 1, 2023
Benjamin R. Lewis, Eric L Garland, Kevin Byrne et al.
60 citations
Psilocybin-assisted psychotherapy shows promise in treating depression and existential distress in people with serious medical illness. However, its individual-based methodology poses challenges for scaling and resource availability. The HOPE trial (A Pilot Study of Psilocybin Enhanced Group Psychotherapy in Patients with Cancer) is an Institutional Review Boards-approved open-label feasibility...
Cross-Cultural Research
August 2, 2023
Jennifer Lau, Yi-Hui Christine Huang, Qinxian Cai et al.
The COVID-19 pandemic and the steps governments took to combat it tormented societies across the globe. Accordingly, existential positive psychologists have emphasized the importance of self-transcendence in mitigating the distress and agony caused by prolonged and rigorous health measures. In this cross-cultural study, the correlation between self-transcendence, people’s confidence in...
August 1, 2023
Gabriel Alexandre Moura, ANA Cecilia de Carvalho Cunha, Beatriz Barros Cordeiro et al.
Objetivo: O uso de psicodélicos em psicoterapia tem sido objeto de interesse crescente na última década.Portanto, o objetivo desta revisão sistemática é examinar a literatura científica mais recente sobre os benefícios do uso de psicodélicos na promoção da saúde mental.Metodologia: Os descritores para essa pesquisa foram selecionados pela Descritores em ciência da saúde (DeCS/MeSH), da...
International Journal of Gynecological Cancer
July 18, 2023
Dan Yaniv, L. Ramondetta, L. Cohen et al.
Women with gynecologic cancers face various physical and psychological challenges throughout their treatment journey. Late stages associated with poor prognosis, along with chronic side effects of treatment, often leave women with existential uncertainty stemming from unpredictable disease trajectory and continuous fear of death. Recently, a patient in her late 30s (JN) with endstage ovarian...
Current opinion in supportive and palliative care
June 1, 2023
Michelle Di Risio, Alison Thompson
5 citations
Within the context of palliative care, existential suffering (ES) can be an exclusive source of suffering or intertwined with physical pain and/or psychological and spiritual suffering. With newly emerging modalities for addressing this phenomenon and its increasing salience given that many patients cite ES as a significant contributing factor to requests for hastened death, a review of recent...
Psychedelic Medicine
June 1, 2023
Noah D Gold, Samantha K. Podrebarac, Lindsay A White et al.
3 citations
More than 50 million people in the United States serve as uncompensated informal caregivers to chronically ill friends or family members. Providing care to a sick loved one can contribute to personal growth but can also cause significant strain. Caregiver distress refers to a constellation of physiological, psychological, interpersonal, and spiritual impairments that typically result when an...