The Journal of Alternative and Complementary Medicine
August 30, 2018
Kaitlin A. Harding, Tracy L. Simpson, David J. Kearney
19 citations
Objectives: Post-traumatic stress disorder (PTSD) and irritable bowel syndrome (IBS) are highly comorbid conditions associated with reduced health-related quality of life. Comorbid prevalence is especially high among veterans, ranging from 23% to 51%, but there is limited research on integrative treatments. Design: To improve treatment of comorbid PTSD and IBS, this study examined the impact of...
JAMA Surgery
August 30, 2018
Carter C Lebares, Amy Hershberger, Ekaterina V. Guvva et al.
135 citations
Importance: Among surgical trainees, burnout and distress are prevalent, but mindfulness has been shown to decrease the risk of depression, suicidal ideation, burnout, and overwhelming stress. In other high-stress populations, formal mindfulness training has been shown to improve mental health, yet this approach has not been tried in surgery. Objective: To test the feasibility and acceptability...
Progress in Neuro-Psychopharmacology and Biological Psychiatry
August 30, 2018
Lanwei Hou, Yirui Qi, Hongwei Sun et al.
Post-traumatic stress disorder (PTSD) is commonly associated with concurrent anxiety and depression symptoms, and reduce the expression of the Brain-Derived Neurotrophic Factor (BDNF) which promotes the proliferation and survival of neurons. The hyperpolarization-activated cyclic nucleotide-gated channel 1(HCN1) could be inhibited by the ketamine, a drug to alleviate depression and anxiety, and...
Trials
August 29, 2018
Yang Zhou, Yuming Peng, Jinghan Fang et al.
Perioperative depressive symptoms (PDS) are common mental comorbidities that influence clinical outcomes and prognosis. However, there is no rapid-acting treatment to address these symptoms during a limited hospital stay. This is a single-center, randomized, placebo-controlled, and double-blind trial. Randomization will be applied and stratified by the severity of PDS (moderate versus severe)....
American Journal of Psychiatry
August 29, 2018
Nolan Williams, Boris D. Heifets, Christine Blasey et al.
510 citations
OBJECTIVE: In addition to N-methyl-d-aspartate receptor antagonism, ketamine produces opioid system activation. The objective of this study was to determine whether opioid receptor antagonism prior to administration of intravenous ketamine attenuates its acute antidepressant or dissociative effects. METHOD: In a proposed double-blind crossover study of 30 adults with treatment-resistant...
National Journal of Research in Ayurved Science
August 23, 2018
Mahesh Kashiram Talekar, Rajesh S Kolarkar
Depression let’s talk- WHO is leading a one-year global campaign on depression. Depression comes under psychiatric disorders. According to WHO healthy person definition is health is complete state of physical, mental and social well-being and not merely the absence of disease or infirmity. Vipassana meditation technique is very useful for balancing of mind. Ä€nÄpÄnasati breathing technique...
Synthesis
August 20, 2018
I. Dimitrov, W. Denny, Jiney Jose
Abstract Ketamine [2-(2-chlorophenyl)-2-(methylamino)cyclohexanone] is a dissociative anaesthetic, first developed in 1963 by Parke-Davis. It finds widespread application in the treatment of battlefield injuries, and in emergency departments for use in children. In recent times the clinical interest in ketamine has increased due to the positive impact it has in treating depression and the rapid...
Translational Behavioral Medicine
August 20, 2018
Jong Y Park, Cecile A Lengacher, R. Reich et al.
Genetic variations of breast cancer survivors (BCS) may contribute to level of residual symptoms, such as depression, stress, fatigue, and cognitive impairment. The objective of this study was to investigate whether particular single-nucleotide polymorphisms (SNPs) moderated symptom improvement resulting from the Mindfulness-Based Stress Reduction for Breast Cancer (MBSR[BC]) program. An...
Frontiers in Psychology
August 17, 2018
Carolina Corthorn
37 citations
The present study evaluated whether mothers’ participation in a mindfulness-based intervention led to statistically significant differences in their general levels of stress, depression, anxiety, parental stress, mindful parenting and mindfulness. Forty-three mothers of preschool-age children participated, 21 in the intervention group and 22 in the comparison group. Scores of mental health...
Journal of Clinical Sleep Medicine
August 15, 2018
M. Gupta, D. Pur
Journal of Clinical Sleep Medicine, Vol. 14, No. 8 August 15, 2018 Creamer and colleagues1 have addressed the very important topic of the high prevalence of clinically significant nightmares (31.2% of 473 military personnel met criteria for nightmare disorder [NDO] and endorsed trouble falling asleep because of bad dreams on at least a weekly basis) among military personnel, with possibly only...