Psycho-oncology
June 1, 2026
L Forest G Rosenfeld, Cecile A Lengacher, Carmen S Rodriguez et al.
Mindfulness-based stress reduction (MBSR) has been shown to decrease stress and fear of cancer recurrence among breast cancer (BC) survivors. However, evidence is lacking in exemplifying MBSR as a method to improve positive, psychosocial outcomes, such as optimism and social support. Enhanced mindfulness has been shown to increase optimism and result in healthier coping strategies, however with...
Psycho-oncology
July 1, 2025
Hongdao Meng, Cecile A Lengacher, Rio Tate et al.
1 citation
To conduct an economic evaluation of a group mindfulness program compared to an education support program for breast cancer survivors (BCS). The cost-utility analysis (cost per quality-adjusted life year [QALY]) was performed from a single-center randomized controlled trial in the United States. Data from 181 BCS were included in the analysis (91 from the mindfulness-based stress reduction for...
Journal of Integrative and Complementary Medicine
April 1, 2025
Cecile A Lengacher, Gizem Hueluer, Julia R. Wang et al.
Introduction: The Mindfulness-Based Stress Reduction program for breast cancer survivors (MBSR [BCs]) is a stress-reducing program designed to increase cognitive functioning through four meditational practices. This randomized clinical trial aimed to determine if improvements in cognitive functioning and perceived cognitive abilities achieved from the MBSR(BC) were mediated through increased...
Innovation in Aging
December 21, 2023
Cecile A Lengacher, Richie Reich
Abstract The purpose of this R01 trial was to evaluate the efficacy of MBSR(BC) compared to the Breast Cancer Education Support program(BCES) or Usual Care(UC) regimens for improvement in cognitive functioning among breast cancer survivors(BCS) who received (CT), or CT and radiation. Methods: BCS (212) were randomized to MBSR(BC) (n=91) or BCES(90) or UC (n = 31) with MBSR(BC) and BCES...
Translational Behavioral Medicine
August 20, 2018
Jong Y Park, Cecile A Lengacher, R. Reich et al.
Genetic variations of breast cancer survivors (BCS) may contribute to level of residual symptoms, such as depression, stress, fatigue, and cognitive impairment. The objective of this study was to investigate whether particular single-nucleotide polymorphisms (SNPs) moderated symptom improvement resulting from the Mindfulness-Based Stress Reduction for Breast Cancer (MBSR[BC]) program. An...
Biological Research for Nursing
August 5, 2018
Cecile A Lengacher, R. Reich, Carly L Paterson et al.
Breast cancer survivors (BCS) often experience psychological and physiological symptoms after cancer treatment. Mindfulness-based stress reduction (MBSR), a complementary and alternative therapy, has reduced subjective measures of stress, anxiety, and fatigue among BCS. Little is known, however, about how MBSR affects objective markers of stress, specifically the stress hormone cortisol and the...
Psycho-oncology
February 1, 2018
Cecile A Lengacher, Richard R Reich, Sophia Ramesar et al.
The purpose of this pilot study was to test the feasibility of delivering the mobile mindfulness-based stress reduction for breast cancer (mMBSR(BC)) program using an iPad and to evaluate its impact on symptom improvement. A single group, pre-posttest design was implemented among female stages 0-III breast cancer survivors (BCS) who completed treatment. Data were collected at baseline and week...
Biological Research for Nursing
January 30, 2014
Cecile A Lengacher, R. Reich, Kevin E Kip et al.
Mindfulness-based stress reduction (MBSR) reduces symptoms of depression, anxiety, and fear of recurrence among breast cancer (BC) survivors. However, the effects of MBSR (BC) on telomere length (TL) and telomerase activity (TA), known markers of cellular aging, psychological stress, and disease risk, are not known. This randomized, wait-listed, controlled study, nested within a larger trial,...
Journal of behavioral medicine
February 2012
Cecile A Lengacher, Richard R Reich, Janice Post-White et al.
To investigate prevalence and severity of symptoms and symptom clustering in breast cancer survivors who attended MBSR(BC). Women were randomly assigned into MBSR(BC) or Usual Care (UC). Eligible women were ≥ 21 years, had been diagnosed with breast cancer and completed treatment within 18 months of enrollment. Symptoms and interference with daily living were measured pre- and post-MBSR(BC)...
Journal of holistic nursing : official journal of the American Holistic Nurses' Association
June 2011
Cecile A Lengacher, Versie Johnson-Mallard, Michelle Barta et al.
To assess the feasibility of whether mindfulness-based stress reduction (MBSR) has a positive effect on breast cancer survivors' psychological status, psychosocial characteristics, symptoms, and quality of life (QOL) during the critical transition period from end of treatment to resumption of daily activities. Single-group, quasi-experimental, pretest-posttest design. A sample of 19 women who...
Psycho-oncology
December 2009
Cecile A Lengacher, Versie Johnson-Mallard, Janice Post-White et al.
Considerable morbidity persists among survivors of breast cancer (BC) including high levels of psychological stress, anxiety, depression, fear of recurrence, and physical symptoms including pain, fatigue, and sleep disturbances, and impaired quality of life. Effective interventions are needed during this difficult transitional period. We conducted a randomized controlled trial of 84 female BC...