Jorjani Biomedicine Journal
August 1, 2018
Rasoul Heshmati
1 citation
Background and objectives: Coronary artery disease (CAD) is associated with negative emotions of anger and stress, which are one of the nonclinical risk factors of the disease.Therefore, evaluation of the effective therapeutic models alleviating the patients' negative emotions is of paramount importance.This study aimed to examine the effect of mindfulness-based stress reduction (MBSR) on anger...
Neuropsychopharmacology
August 2018
Josephine C McGowan, Collin Hill, Alessia Mastrodonato et al.
Recently, we have shown that ketamine given prior to stress exposure protects against the development of depressive-like behavior in mice. These data suggest that it may be possible to prevent the induction of affective disorders before they develop by administering prophylactic pharmaceuticals, a relatively nascent and unexplored strategy for psychiatry. Here, we performed metabolomics...
The International Journal of Neuropsychopharmacology
August 1, 2018
Shabah Mohammad Shadli, Tame Kawe, Daniel Martin et al.
Ketamine is swiftly effective in a range of neurotic disorders that are resistant to conventional antidepressant and anxiolytic drugs. The neural basis for its therapeutic action is unknown. Here we report the effects of ketamine on the EEG of patients with treatment-resistant generalized anxiety and social anxiety disorders. Twelve patients with refractory DSM-IV generalized anxiety disorder...
Current Opinion in Anaesthesiology
August 2018
Kathryn Cobb, Monika Nanda
Anesthetics, such as thiopental, methohexital, propofol and ketamine have been used to induce unconsciousness for electroconvulsive therapy (ECT), each with its advantages and disadvantages. Only until recently was it discovered that ketamine may have inherent antidepressant effects. We reviewed the side effect profile of ketamine and examined the literature for whether or not ketamine augments...
Neuropsychopharmacology
August 2018
Jun-Ichi Yamaguchi, Hidetoh Toki, Youge Qu et al.
(R,S)-Ketamine has rapid and sustained antidepressant effects in depressed patients. Although the metabolism of (R,S)-ketamine to (2 R,6 R)-hydroxynorketamine (HNK), a metabolite of (R)-ketamine, has been reported to be essential for its antidepressant effects, recent evidence suggests otherwise. The present study investigated the role of the metabolism of (R)-ketamine to (2 R,6 R)-HNK in the...
European Neuropsychopharmacology
August 2018
Lucie Bartova, Konstantinos Papageorgiou, Ivan Milenkovic et al.
Rapid anti-suicidal and antidepressant effects of ketamine have repeatedly been confirmed in unipolar and bipolar depression. Although meaningful antidepressant efficacy of ketamine has also been shown in depressed patients with a history of psychotic symptoms, its administration in psychotic disorders has largely been neglected due to its potential to exacerbate dissociative or psychotic...
Australian & New Zealand Journal of Psychiatry
August 2018
Emily Hielscher, Melissa Connell, David W. Lawrence et al.
Despite growing literature on psychotic experiences, no nationally representative study has reported on the prevalence of both hallucinatory experiences and delusional experiences in Australian adolescents. Also, while many studies have examined the association between psychotic experiences and certain demographic and clinical correlates, there are more variables of interest to be investigated,...
August 1, 2018
Josiane Bourque
Cette thèse fait la promotion d’une nouvelle approche ciblant le risque de psychose qui consiste à identifier les enfants et les jeunes adolescents de la communauté appartenant à différentes trajectoires développementales d’expériences psychotiques. Une identification très précoce du risque de psychose chez des jeunes de la communauté pourrait ainsi diminuer la période où les symptômes...
Complementary Therapies in Medicine
August 1, 2018
Simone S Nascimento, Larissa R Oliveira, Josimari M DeSantana
There are different ways of dealing with pain and cognitive and meditative therapies (CMT) are alternative ways to regulate the emotions associated with pain. Current studies apply neuroimaging techniques trying to elucidate the neural mechanisms of cognitive strategies for pain. This systematic review aimed to summarize the evidence on brain activity changes after CMT, which include cognitive...
Brain and Cognition
August 1, 2018
F. Travis, Laurent Valosek, Artie Konrad et al.
Background: Psychological stability and brain integration are important factors related to physical and mental health and organization effectiveness. This study tested whether a mind‐body technique, the Transcendental Meditation (TM) program could increase EEG brain integration and positive affect, and decrease psychological distress in government employees. Method: Ninety‐six central office...