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Depression: all studies

Page 798 of 1,034: studies 7,971 to 7,980 of 10,336, newest first. Back to the depression overview

Research

Supporting the Patient on LSD Day

AJN, American Journal of Nursing May 19, 2021 Betsy Todd

Editor's note: From its first issue in 1900 through to the present day, AJN has unparalleled archives detailing nurses' work and lives over more than a century. These articles not only chronicle nursing's growth as a profession within the context of the events of the day, but also reveal prevailing societal attitudes about women, health care, and human rights. Today's nursing school curricula...

AJN On the Cover

AJN, American Journal of Nursing May 19, 2021 Diane Szulecki

Figure: This month's cover features a colorized magnetic resonance imaging scan of a human brain—a nod to Penn and colleagues' article “Psychedelic-Assisted Therapy,” which presents an overview of a growing field that nurses are positioned to be part of. Photo by Daisy Daisy / Shutterstock.This month's cover features a colorized magnetic resonance imaging scan of a human brain—a nod to Penn and...

Future Directions for Clinical Psilocybin Research: The Relaxed Symptom Network

May 19, 2021 Evan Lewis-Healey, Ruben Laukkonen, Michiel van Elk 4 citations preprint

Objective: Recent clinical trials have demonstrated that psilocybin may have strong antidepressant effects, and may be effective in the treatment of depressive disorders when embedded in a psychotherapeutic protocol (psilocybin-assisted psychotherapy; PAP). However, despite promising results, the mechanism(s) that may be responsible for the antidepressant effects of PAP remain contested. Within...

Susceptibility of Women to Cardiovascular Disease and the Prevention Potential of Mind–Body Intervention by Changes in Neural Circuits and Cardiovascular Physiology

Biomolecules May 10, 2021 Hyun‐Jeong Yang, Eugene Koh, Yunjeong Kang 29 citations

Women have been reported to be more vulnerable to the development, prognosis and mortality of cardiovascular diseases, yet the understanding of the underlying mechanisms and strategies to overcome them are still relatively undeveloped. Studies show that women's brains are more sensitive to factors affecting mental health such as depression and stress than men's brains. In women, poor mental...

The Safety, Clinical, and Neurophysiological Effects of Intranasal Ketamine in Patients Who Do Not Respond to Electroconvulsive Therapy: Protocol for a Pilot, Open-Label Clinical Trial

JMIR Research Protocols May 10, 2021 Yuliya Knyahnytska, Daniel M. Blumberger, Tyler S Kaster et al.

Background Major depressive disorder is among the most disabling illnesses worldwide, with a lifetime prevalence of 16.2%. Research suggests that 20% to 40% of patients with depression do not respond to pharmacotherapy, developing treatment-resistant depression. Electroconvulsive therapy is the gold standard for treating individuals with treatment-resistant depression, with remission rates of...

Gut Microbiota Associated With Effectiveness And Responsiveness to Mindfulness-Based Cognitive Therapy in Improving Trait Anxiety

Frontiers in Cellular and Infection Microbiology May 10, 2021 Zonghua Wang, Xiaoxiao Xu, Shuang Liu et al.

Objective Mindfulness-based interventions have been widely demonstrated to be effective in reducing stress, alleviating mood disorders, and improving quality of life; however, the underlying mechanisms remained to be fully understood. Along with the advanced research in the microbiota-gut-brain axis, this study aimed to explore the impact of gut microbiota on the effectiveness and...

The anterior cingulate cortex as a key locus of ketamine’s antidepressant action

Neuroscience & Biobehavioral Reviews May 10, 2021 Laith Alexander, Luke A. Jelen, Mitul A. Mehta et al. 79 citations

The subdivisions of the anterior cingulate cortex (ACC) - including subgenual, perigenual and dorsal zones - are implicated in the etiology, pathogenesis and treatment of major depression. We review an emerging body of evidence which suggests that changes in ACC activity are critically important in mediating the antidepressant effects of ketamine, the prototypical member of an emerging class of...

DOI: 10.1016/j.neubiorev.2021.05.003 (opens in new tab) Ketamine Antidepressant Anterior cingulate cortex Cognition +2

Which is the best way of using nitrous oxide for treatment and research in neuropsychiatry?

Revista Brasileira de Psiquiatria May 10, 2021 M. Gillman

I welcome the excellent paper by Guimarães et al. which extends research on nitrous oxide (N2O) in neuropsychiatry – a neglected field, since our initial work in 1982 and then 1985 indicating that low, anxiolytic, and non-anaesthetic doses of N2O ameliorate depression. 3 Research has demonstrated that N2O, at subanaesthetic concentrations acts on opioid receptors. We therefore concluded that...

A Pilot Randomized Clinical Trial of Mindfulness-Oriented Recovery Enhancement as an Adjunct to Methadone Treatment for People with Opioid Use Disorder and Chronic Pain: Impact on Illicit Drug Use, Health, and Well-Being

Journal of Substance Abuse Treatment May 8, 2021 Nina A Cooperman, Adam W. Hanley, Anna Kline et al.

Background: Chronic pain is highly prevalent among people in methadone maintenance treatment (MMT) for opioid use disorder and is known to be an important contributor to treatment discontinuation and opioid relapse. Mindfulness-Oriented Recovery Enhancement (MORE) is one of the few interventions developed and tested as an integrated treatment to simultaneously address both pain and illicit...