AJN, American Journal of Nursing
May 19, 2021
Betsy Todd
Editor's note: From its first issue in 1900 through to the present day, AJN has unparalleled archives detailing nurses' work and lives over more than a century. These articles not only chronicle nursing's growth as a profession within the context of the events of the day, but also reveal prevailing societal attitudes about women, health care, and human rights. Today's nursing school curricula...
AJN, American Journal of Nursing
May 19, 2021
Diane Szulecki
Figure: This month's cover features a colorized magnetic resonance imaging scan of a human brain—a nod to Penn and colleagues' article “Psychedelic-Assisted Therapy,” which presents an overview of a growing field that nurses are positioned to be part of. Photo by Daisy Daisy / Shutterstock.This month's cover features a colorized magnetic resonance imaging scan of a human brain—a nod to Penn and...
May 19, 2021
Evan Lewis-Healey, Ruben Laukkonen, Michiel van Elk
4 citations
preprint
Objective: Recent clinical trials have demonstrated that psilocybin may have strong antidepressant effects, and may be effective in the treatment of depressive disorders when embedded in a psychotherapeutic protocol (psilocybin-assisted psychotherapy; PAP). However, despite promising results, the mechanism(s) that may be responsible for the antidepressant effects of PAP remain contested. Within...
May 12, 2021
Ioana A. Cristea, Florian Naudet, Clara Miguel
1 citation
preprint
Letter to the editor in reference to Carhart-Harris R, Giribaldi B, Watts R, et al. Trial of Psilocybin versus Escitalopram for Depression. The New England journal of medicine 2021;384:1402-11.
Biomolecules
May 10, 2021
Hyun‐Jeong Yang, Eugene Koh, Yunjeong Kang
29 citations
Women have been reported to be more vulnerable to the development, prognosis and mortality of cardiovascular diseases, yet the understanding of the underlying mechanisms and strategies to overcome them are still relatively undeveloped. Studies show that women's brains are more sensitive to factors affecting mental health such as depression and stress than men's brains. In women, poor mental...
JMIR Research Protocols
May 10, 2021
Yuliya Knyahnytska, Daniel M. Blumberger, Tyler S Kaster et al.
Background Major depressive disorder is among the most disabling illnesses worldwide, with a lifetime prevalence of 16.2%. Research suggests that 20% to 40% of patients with depression do not respond to pharmacotherapy, developing treatment-resistant depression. Electroconvulsive therapy is the gold standard for treating individuals with treatment-resistant depression, with remission rates of...
Frontiers in Cellular and Infection Microbiology
May 10, 2021
Zonghua Wang, Xiaoxiao Xu, Shuang Liu et al.
Objective Mindfulness-based interventions have been widely demonstrated to be effective in reducing stress, alleviating mood disorders, and improving quality of life; however, the underlying mechanisms remained to be fully understood. Along with the advanced research in the microbiota-gut-brain axis, this study aimed to explore the impact of gut microbiota on the effectiveness and...
Neuroscience & Biobehavioral Reviews
May 10, 2021
Laith Alexander, Luke A. Jelen, Mitul A. Mehta et al.
79 citations
The subdivisions of the anterior cingulate cortex (ACC) - including subgenual, perigenual and dorsal zones - are implicated in the etiology, pathogenesis and treatment of major depression. We review an emerging body of evidence which suggests that changes in ACC activity are critically important in mediating the antidepressant effects of ketamine, the prototypical member of an emerging class of...
Revista Brasileira de Psiquiatria
May 10, 2021
M. Gillman
I welcome the excellent paper by Guimarães et al. which extends research on nitrous oxide (N2O) in neuropsychiatry – a neglected field, since our initial work in 1982 and then 1985 indicating that low, anxiolytic, and non-anaesthetic doses of N2O ameliorate depression. 3 Research has demonstrated that N2O, at subanaesthetic concentrations acts on opioid receptors. We therefore concluded that...
Journal of Substance Abuse Treatment
May 8, 2021
Nina A Cooperman, Adam W. Hanley, Anna Kline et al.
Background: Chronic pain is highly prevalent among people in methadone maintenance treatment (MMT) for opioid use disorder and is known to be an important contributor to treatment discontinuation and opioid relapse. Mindfulness-Oriented Recovery Enhancement (MORE) is one of the few interventions developed and tested as an integrated treatment to simultaneously address both pain and illicit...