Basic pain research has shed light on key cellular and molecular mechanisms underlying nociceptive and phenomenological aspects of pain. Despite these advances, we still yearn for the discovery of novel therapeutic strategies to address the unmet needs of about 70 % of chronic neuropathic pain patients whose pain fails to respond to opioids as well as to other conventional analgesic agents....
Abstract Background Holotropic breathwork (Grof ® Breathwork), was developed by Stanislav Grof and Christina Grof as a ‘non-drug’ alternative technique to evoke altered states of consciousness (ASC). Interestingly, although HBW has been anecdotally reported to evoke experiences and mental health effects corresponding to those of psychedelic substances, the scientific literature on the matter is...
This study comprehensively summarizes research in the field of meditation, especially mindfulness meditation from 1900 to 2021, by analyzing the knowledge map through CiteSpace and VOSviewer software. Using “mindfulness *” or “meditation *” as the topic, articles included in the Science Citation Index Expanded and Social Sciences Citation Index were searched in the web of science core database,...
Background: Mindfulness interventions are increasingly popular as an approach to improve mental well-being. To date, no Cochrane Review examines the effectiveness of mindfulness in medical students and junior doctors. Thus, questions remain regarding the efficacy of mindfulness interventions as a preventative mechanism in this population, which is at high risk for poor mental health....
December 8, 2021Cesare Lino, Stefan Neuwersch-Sommeregger, R. Likar et al.
preprint
Objective: To investigate the effectiveness of Mindfulness-Based Pain Therapy (MBPT) a treatment combining mindfulness meditation and several interventions taken from cognitive therapy within the frame of the multimodal pain therapy program, in patients suffering from chronic low back pain (CLBP).Design: A quasi-randomized case-control study. Subjects: The study included 20 subjects with...
Psychedelic-assisted therapy research for depression and PTSD has been fast tracked in the United States with the Food and Drugs Administration (FDA) granting breakthrough designations for MDMA (post-traumatic stress disorder) and psilocybin (major depressive disorder). The psychotherapeutic treatments accompanying these psychedelics have not been well-studied and remain controversial. This...
Cannabis abuse is a common public health issue and may lead to considerable adverse effects. Along with other effects, the dependence on cannabis consumption is a serious problem which has significant consequences on biochemical and clinical symptoms. This study intends to evaluate the harmful effects of the use of cannabis on thyroid hormonal levels, cardiovascular indicators, and psychotic...
CultureDecember 2, 2021Wolfgang G. Jilek1 citation
The author presents examples of pathogenic influence of culture. He identifies specific pathogenic factors associated with rapid socio-cultural change affecting North American Indians and African populations and sketches the resulting typical psychopathological conditions: anomic depression in Amerindians, transient psychotic reactions (bouffée délirante) in Africans. Witchcraft and sorcery...
Background: The therapeutic options for neurobehavioral disorders are still limited, and in many cases, they lack a satisfactory balance between efficacy and side effects. Objective: This work aims to review current evidence regarding the potential contribution of psychedelics and hallucinogens to the discovery of new drugs for treating different psychiatric disorders. Discussion:...
This chapter discusses the spiritual and psychosocial aspects of care using a narrative approach. It suggests that far more suffering in patients with advanced illness results from psychic rather than from physical distress, assuming physical symptoms are reasonably palliated. Categories of psychic distress described include depression, anxiety, and delirium. A discussion of anticipatory and...