Multiple Sclerosis Journal
June 1, 2025
Mark P Jensen, Susan Robles, Michael G Nash et al.
1 citation
Fatigue is a common problem in individuals with multiple sclerosis (MS). The objective was to evaluate the effects on fatigue of having 4 weeks of access to audio recordings of therapeutic hypnosis (HYP) and mindfulness meditation (MM) practices. A total of 333 individuals with MS and fatigue were randomly assigned to one of the three treatment conditions for 28 weeks: (1) access to therapeutic...
Stress and Health
June 1, 2025
Esther N. Moszeik, Nicolas Rohleder, Karl-Heinz Renner
10 citations
Yoga Nidra meditation has been increasingly examined in recent years for its potential to enhance psychological well-being. However, few studies have examined its biological effects-such as diurnal cortisol patterns particularly in larger samples using pre-post designs. The primary objective of this randomised controlled trial was to examine both the psychological (stress, anxiety, depression,...
Indian Journal of Psychiatry
June 1, 2025
Dushad Ram, Akash Mathew
4 citations
Psychological, social, and cultural factors influence the development of dissociative and conversion disorders. India, with its diverse cultural beliefs and socioeconomic disparities, provides a unique setting for studying the clinical presentations of these disorders. This scoping review synthesizes literature on dissociative and conversion disorders in India, focusing on their...
Psychedelic Medicine
June 1, 2025
Sara Shoar, Alissa Bazinet, Chaitra Jairaj
2 citations
In recent years, there has been a resurgence in research exploring the therapeutic potential of psychedelics for treating mental health disorders, coinciding with increasing psychedelic use and changing legal landscapes in the United States and globally. Despite these shifts, there remains a notable gap in understanding related to the safety of psychedelic use during critical stages of the...
Cureus
June 1, 2025
Shaheen E. Lakhan
2 citations
Do-it-yourself (DIY) brain hacking has evolved from fringe experimentation to a cultural and clinical phenomenon reshaping how individuals interact with their brains. From early self-directed use of racetam nootropics, at-home transcranial direct current stimulation, and meditation apps, to the normalization of microdosing psychedelics, this movement reflects a broader shift toward brain...
Indian journal of microbiology
June 1, 2025
Balakrishnan Karthiyayini, Nalliah Nithya Kalyani, Balakrishnan Gowdhami et al.
2 citations
The antimicrobial compound psilocybin possesses psychoactive properties with therapeutic applications. Psilocybin is the main component naturally present in psychedelic mushrooms and has been utilized in the treatment of depression and neurological disorders. In this study, psychedelic mushrooms were collected from Kodaikanal, Tamil Nadu. They underwent solvent extraction using High Performance...
Psychedelic Medicine
June 1, 2025
Sierra Carter, Grace Packard, Jessica L Maples-Keller
Black Americans are significantly underrepresented in psychedelic trials despite significant mental health disparities. Growing research suggests that psychedelic-assisted therapy (PAT) is an effective treatment for post-traumatic stress disorder and depression. It is important to understand perceptions of PAT among populations with unmet mental health needs. We conducted four focus groups to...
Molecular Psychiatry
June 1, 2025
Anderson Camargo, Anna Nilsson, Reza Shariatgorji et al.
5 citations
Ketamine may be a novel pharmacologic approach to enhance resilience and protect against stress-related disorders, but the molecular targets underlying this response remain to be fully characterized. The multifunctional protein p11 is crucial in the pathophysiology of depression and antidepressant responses. However, it is still unclear whether p11 plays a role in the pro-resilience effects...
Current Opinion in Neurology
June 1, 2025
Maurizio Severino, Mark W Green
The scope of this review is to discuss persistent aura without infarction, a rare, highly disabling, yet apparently benign clinical condition, straddling neurology, neuro-ophthalmology, and psychiatry, whose differential diagnosis is essential for an appropriate therapeutic approach and to avoid clinical complications. Here we attempt to report on the available literature, trying to present a...
Expert Opinion on Therapeutic Targets
June 1, 2025
Naomi Xiao, Liyang Yin, Kayla M Teopiz et al.
5 citations
The mechanism of action of antidepressants is not fully ascertained. In addition to monoamines, disparate other effectors are also implicated in the molecular and cellular effects of chronic stress including neurogenesis, neurodifferentiation, and neuroplasticity. Evidence suggests sigma-1 receptors (S1Rs) as a putative target and possible mediator of antidepressant activity. Data from...