The journal of pain
January 6, 2026
Mark P Jensen, Marcia A Ciol, Kevin J Gertz et al.
Psychological interventions have reliable but modest effects on chronic pain outcomes, but our understanding of the mechanisms that underlie these effects remains limited. This paper presents the findings from a series of secondary analyses using data from a randomized clinical trial (clinicalTrials.gov, NCT02653664). Three hundred and twenty-eight Veterans of the US Armed Forces with chronic...
The journal of pain
July 1, 2025
Ingrid Bindicsova, Leanne M Hides, Katherine Brain et al.
1 citation
The purpose of this pilot randomized controlled trial was to examine the feasibility of an internet delivered, self-directed mindfulness-based cognitive therapy (iMBCT) program compared to a delayed treatment (DT) control. This trial employed a 2-group parallel (1:1), design and was pre-registered (ANZCTR Identifier: 12623000833662). Participants were N = 48 adults with chronic pain, randomized...
Multiple sclerosis (Houndmills, Basingstoke, England)
June 1, 2025
Mark P Jensen, Susan Robles, Michael G Nash et al.
1 citation
Fatigue is a common problem in individuals with multiple sclerosis (MS). The objective was to evaluate the effects on fatigue of having 4 weeks of access to audio recordings of therapeutic hypnosis (HYP) and mindfulness meditation (MM) practices. A total of 333 individuals with MS and fatigue were randomly assigned to one of the three treatment conditions for 28 weeks: (1) access to therapeutic...
Pain
February 1, 2025
James Gerhart, John W Burns, Beverly E Thorn et al.
3 citations
Findings suggest that cognitive therapy (CT), mindfulness-based stress reduction (MBSR), and behavior therapy (BT) for chronic pain produce improvements through changes in putative mechanisms. Evidence supporting this notion is largely based on findings showing significant associations between treatment mechanism variables and outcomes. An alternative view is that treatments may work by...
Rehabilitation psychology
February 1, 2025
Erica J Ho, Aaron P Turner, Mark P Jensen et al.
1 citation
Clinical trials often focus on symptom reduction as a primary outcome, overlooking positive psychology factors of potential importance although many individuals can and do live well with pain. The Patient-Reported Outcomes Measurement Information System (PROMIS) Psychosocial Illness Impact-Positive (PIIP) scale assesses perceptions of adaptive psychosocial functioning (e.g., coping and...
Journal of Pain & Palliative Care Pharmacotherapy
September 1, 2024
Melissa A Day, Natasha Matthews, Jonathan N. Davies et al.
This study investigated the analgesic effects of a single session of mindfulness meditation (MM) and loving-kindness meditation (LKM) relative to a control. A total of 100 adults with chronic or current problematic pain completed a survey and were randomized to a 20-minute MM, LKM, or audiobook control. Co-primary outcomes of pain intensity and unpleasantness and mediators of mindfulness and...
BMC Medicine
April 12, 2024
Melissa A Day, Marcia A Ciol, M Elena Mendoza et al.
9 citations
Chronic low back pain (CLBP) is a significant problem affecting millions of people worldwide. Three widely implemented psychological techniques used for CLBP management are cognitive therapy (CT), mindfulness meditation (MM), and behavioral activation (BA). This study aimed to evaluate the relative immediate (pre- to post-treatment) and longer term (pre-treatment to 3- and 6-month follow-ups)...
Rehabilitation psychology
August 1, 2023
Aaron P Turner, Karlyn A Edwards, Mark P Jensen et al.
5 citations
To examine the impact of three behavioral interventions for chronic pain on substance use. Participants were 328 Veterans with chronic pain receiving care at one of two Veterans Affairs Medical Centers in the northwest United States. Participants were randomly assigned to one of three 8-week manualized in-person group treatments: (a) hypnosis (HYP), (b) mindfulness meditation (MM), or (c)...
Journal of Pain Research
2022
Alexandra Ferreira-Valente, Benjamin P Van Dyke, Melissa A Day et al.
Previous research supports the usefulness of hypnosis (HYP), mindfulness meditation (MM), and prayer as pain self-management strategies in adults with chronic pain. However, their effects on acute pain have been less researched, and no previous head-to-head study compared the immediate effects of these three approaches on pain-related outcomes. This study compared the immediate effects of HYP,...
The Clinical Journal of Pain
October 1, 2020
Melissa A Day, L. Charles Ward, Beverly E Thorn et al.
Objectives: This study evaluated theoretically derived mechanisms and common therapeutic factors to test their role in accounting for pain-related outcome change during group-delivered cognitive therapy, mindfulness meditation, and mindfulness-based cognitive therapy for chronic low back pain. Methods: A secondary analysis of a pilot randomized controlled trial was used to explore the primary...
Pain Medicine
November 1, 2019
Melissa A Day, L Charles Ward, Dawn M Ehde et al.
AbstractObjectiveThis pilot trial compared the feasibility, tolerability, acceptability, and effects of group-delivered mindfulness meditation (MM), cognitive therapy (CT), and mindfulness-based cognitive therapy (MBCT) for chronic low back pain (CLBP).SettingUniversity of Queensland Psychology Clinic.SubjectsParticipants were N = 69 (intent-to-treat [ITT] sample) adults with CLBP.DesignA...
Pain medicine (Malden, Mass.)
December 1, 2014
Mark P Jensen, Leslie H Sherlin, Felipe Fregni et al.
The objective of this study was to examine the associations between baseline electroencephalogram (EEG)-assessed brain oscillations and subsequent response to four neuromodulatory treatments. Based on available research, we hypothesized that baseline theta oscillations would prospectively predict response to hypnotic analgesia. Analyses involving other oscillations and the other treatments...