Fibromyalgia syndrome (FMS) is a chronic condition characterized by widespread pain and tenderness at specific points in the body, sleep disturbances, fatigue, depression, and anxiety. Current management for FMS focuses on a multidisciplinary approach to symptom management. Among the complementary and alternative therapies used for symptom management, yoga holds a significant position. Yoga,...
Abstract Introduction Targeted Dream Incubation (TDI) is the process of utilizing verbal cues (such as, “while you try to fall asleep, try and think of a tree”) during pre-sleep stages in order to directly shape dream content. Preliminary results have demonstrated that TDI may be able to increase dreaming self-efficacy (DSE). Our study aimed to replicate and extend initial findings by examining...
Nitrous oxide (N2O), an anesthetic gas used for dental procedures, has recently become increasingly recognized as a potential drug of misuse and abuse, with an increasing number of case studies reporting serious adverse effects, including megaloblastic anemia, myelopathy, neuropathy, subacute combined degeneration, psychosis, and even death. There is also growing research support for the use of...
Background: Patients with refractory conditions often identify themselves with their illness, which affects multiple aspects of their lives. The pictorial representation of illness and self measure (PRISM) is a tool used to assess the enmeshment of individuals' perception of self with a particular medical condition, broadly termed self-condition enmeshment. Aims: This study aimed to evaluate...
Abstract This is the first book to explore the use of psychedelic medicines in palliative care and addiction medicine. Bringing together a diverse team of palliative physicians, therapists, researchers, spiritual guides, and entrepreneurs, the book explores the history, cultural significance, science, and legal status of eight major psychedelic medications. Each medication holds fascinating...
May 1, 2025Angelica Ukaigwe, Abhishek Chauhan, S. Vinod Kumar
Abstract 5-Methoxy-N,N-dimethyltryptamine (5-MeO-DMT) is a psychoactive compound found in the parotid gland venom of the Sonoran Desert toad, Incilius alvarius, and certain seeds, leaves, and barks within the Amazonian rainforest. Similar to DMT containing ayahuasca, 5-MeO-DMT has become newly integrated as a spiritual sacrament in certain churches, offering a psychedelic experience to process...
Abstract Introduction Research on psychedelic use and sleep satisfaction remains unclear despite increased use. This study examines the psychedelic use and sleep satisfaction among 18-to-35-year-olds enrolled in the Herbal Heart Study. Methods The exposure variables were lifetime self-reported use of any psychedelic (LSD, psilocybin, peyote, mescaline, ayahuasca/DMT) and psilocybin-alone. Sleep...
May 1, 2025Jessi Humphreys, Lou Lukas, Yvan Beaussant et al.
Abstract Psilocybin, a naturally occurring psychoactive compound found in more than 200 mushroom species, has an enduring history of use in sacred rituals of Indigenous healers worldwide. With selective serotonin receptor binding, activation of the serotonergic neurological system enables psilocybin to potentiate neuroplasticity, enabling individuals to engage in meaning-making from psychedelic...
Contemporary Clinical TrialsMay 1, 2025Juliette Faure-De Baets, Jeremy Besnard, Frédéric Banville et al.3 citations
Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease primarily affecting motor neurons but also leading to significant non-motor symptoms, including cognitive impairments, anxiety, depression, and behavioral changes, which severely impact quality of life. While mindfulness-based interventions (MBIs) have shown promise in alleviating psychological distress, their accessibility is...