ABSTRACT: Depression is a common disorder experienced by people living with HIV (PLHIV), negatively affecting their quality of life and treatment adherence. Mindfulness-Based Cognitive Therapy (MBCT) has been developed to help individuals cope with depression by enhancing awareness and acceptance of present experiences. This study aimed to evaluate the effectiveness of MBCT in reducing...
Background/Objectives: Caring for a child with Autism Spectrum Disorder (ASD) is often associated with elevated psychological distress and reduced life satisfaction. Mindfulness-based interventions may offer substantial benefits by enhancing emotion regulation, reducing maladaptive cognitive patterns, and strengthening mindful parenting. This randomized controlled trial (RCT) examined the...
Farmacja PolskaDecember 30, 2025Ewa Niedzielska-Andres, Angelika Ziaja, Stanisław Zielinski et al.
Przedmiot badań: W ostatnich latach obserwuje się rosnące zainteresowanie wykorzystaniem naturalnych halucynogenów w leczeniu zaburzeń psychicznych, uzależnień czy bólu. Substancje takie jak psylocybina, ayahuasca, ibogaina czy meskalina poddawane są ocenie w badaniach klinicznych, które wskazują na ich potencjał terapeutyczny, zwłaszcza w leczeniu depresji lekoopornej, zespołu stresu...
BPL-003 is a novel investigational psychedelic compound being developed for the treatment-resistant depression (TRD). Its active ingredient, 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT), is a serotonergic psychedelic with preferential agonism at 5-HT1A receptors and rapid pharmacokinetics, allowing for a brief, supervised in-clinic administration. Preclinical studies demonstrate that 5-MeO-DMT...
Abstract Objective Child and adolescent depression is an increasing concern, significantly impacting their emotional, academic, and social well-being. While mindfulness-based interventions have shown effectiveness in reducing depressive symptoms, emerging technologies like virtual reality offer more engaging approaches. This study aimed to investigate the moderating effects of a virtual...
The primary aim of this review was to investigate the specific cognitive and neural effects of mindfulness practices on veridical and false episodic memory and the impact of these effects on memory in clinical populations. A scoping review was conducted to assess and synthesize this recent research, focusing on 26 papers from 2010 to 2024 on the topic of mindfulness and human episodic memory....
Background/Objectives: Incarcerated people experience high rates of trauma, psychological distress, and social marginalization. Yoga has been introduced in prisons as a trauma-sensitive mind-body practice, yet its rehabilitative contribution remains uncertain. This systematic review aimed to synthesize evidence on the feasibility and effectiveness of yoga interventions delivered in correctional...
Los acontecimientos estresantes afectan regularmente a las personas a lo largo de sus vidas. Las intervenciones basadas en mindfulness pueden utilizarse para prevenir las consecuencias negativas de estos acontecimientos. El presente estudio pretende evaluar el impacto de una intervención de mindfulness breve, midiendo sus efectos sobre la sintomatología depresiva, la satisfacción con la vida,...
This study piloted and validated the Russian-language version of R. W. Hood’s Mysticism Scale in an adult sample. Two comparable groups participated (N = 200; age 19–61): 100 with self-reported mystical/transcendent experiences and 100 without such experiences. The adaptation used forward–back translation with expert review. Psychometrics included exploratory factor analysis (KMO = 0.86;...
) that has a unique therapeutic potential across multiple indications, including opioid dependence, substance use disorders, depression, anxiety, posttraumatic stress disorder (PTSD), and traumatic brain injury (TBI). We systematically examined the effects of ibogaine, its main metabolite noribogaine, and a series of iboga analogs at monoamine neurotransmitter transporters, some of which have...