Meditation has increasingly been recognized as a helpful non-pharmacological intervention to treat psychological stress, anxiety, and depression during pregnancy-a period that plays a significant role in maternal and fetal health. Although very popular, there is very little scientific evidence on how brief audio meditation affects brain activity in pregnant women. This work reports an EEG-based...
The prefrontal cortex is central to executive function, emotional regulation, and top-down control of limbic structures, particularly the amygdala. Dysregulation of prefrontal-limbic connectivity is implicated in anxiety, depression, and stress-related disorders. Contemplative practices enhance prefrontal regulation and reduce limbic reactivity, promoting emotional resilience. Prostration...
medRxiv Preprint ServerMarch 31, 2026Maia Mallevays, Louise Fuet, Michel Danon et al.1 citation
preprint
Esketamine is a fast-acting antidepressant drug which induces acute psychoactive effects. The most frequent is a dissociative state which seems unrelated to therapeutic efficacy. Other esketamine-induced effects, including psychedelic-like mystical experiences, have been poorly studied in terms of phenomenology and frequency, and may carry specific therapeutic relevance. In this study, we...
Abstract Background To our knowledge, no detailed dissociative fugue cases have been reported from any Arab nation in the indexed literature, despite comprehensive searches across international databases and regional Arabic-language sources. Applied to the Arab world’s 492-million population, even conservative prevalence estimates suggest substantial numbers of undiagnosed cases, indicating...
HRMARS - Workplace mental health challenges are increasingly prevalent in high-pressure industries, particularly within the information technology (IT) sector. Working women face compounded stressors due to professional demands and socio-cultural expectations, placing them at heightened risk of psychological distress. Mindfulness has been widely recognized as a protective factor that enhances...
Background: Pregnancy is a critical life stage characterized by physiological and psychosocial changes that increase vulnerability to mental health disorders such as depression, anxiety, and fear of childbirth. Objective: To identify Mindfulness-Based Childbirth and Parenting (MBCP) as an intervention for reducing depression, anxiety, stress, and fear of childbirth, as well as enhancing...
Individuals living with HIV frequently experience elevated depressive symptoms due to chronic stress, stigma, and emotional burden. Compassion-based interventions such as Loving-Kindness and Self-Compassion Meditation (LKCM) have the potential to improve emotional well-being, yet evidence in HIV-positive populations remains limited. This study examined the preliminary effects of a brief...
Abstract Introduction While the relationship between substance use disorders (SUD) and mental health conditions is well established, treatment for these co-occurring conditions is difficult to manage. Research on the potential for psychedelic treatments to address SUD and mental health conditions has recently seen a resurgence. This study aimed to explore narratives on the influence of...
Major depressive disorder remains a leading cause of disability worldwide, and current antidepressants are limited by delayed onset and incomplete response. Building on advances driven by ketamine research, renewed interest has focused on classical serotonergic psychedelics—particularly psilocybin, N,N-dimethyltryptamine (DMT), 5-methoxy-DMT, and lysergic acid diethylamide (LSD)—which, under...
Australia recently down-scheduled and authorised psychedelic-assisted therapies, including psilocybin, for certain mental health conditions. Evidence is emerging for potential application in substance use disorder treatment. However, regulatory developments have outpaced implementation readiness. While service leaders and clinicians are crucial to implementation, little research examines their...