Ketamine, a dissociative anesthetic introduced in the 1960s, has re-emerged as a versatile therapeutic agent extending beyond its traditional perioperative role. Its rapid antidepressant action in treatment-resistant depression and efficacy in acute and chronic pain syndromes have driven what is termed the “ketamine renaissance.” Unlike conventional monoaminergic antidepressants, ketamine...
The prefrontal cortex is central to executive function, emotional regulation, and top-down control of limbic structures, particularly the amygdala. Dysregulation of prefrontal-limbic connectivity is implicated in anxiety, depression, and stress-related disorders. Contemplative practices enhance prefrontal regulation and reduce limbic reactivity, promoting emotional resilience. Prostration...
Background: Medical students often experience significant psychological stress, which can negatively impact their academic performance, cognitive functions, and overall well-being. Psychological/emotional stress can also affect hearing if severe or if it lasts long enough. Amongst stress reduction strategies, meditation techniques are found to be helpful. Aims and Objectives: This study aimed...