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Depression: all studies

Page 327 of 1,036: studies 3,261 to 3,270 of 10,358, newest first. Back to the depression overview

Research

The effects of a mindfulness-based intervention on primary school students’ symptoms of inattention, depression, and anxiety: A moderated mediation examination

Catherine Malboeuf-Hurtubise, Geneviève Taylor, Terra Léger-Goodes et al. preprint

Abstract The number of mindfulness-based interventions has proliferated in the last decade as accessible evidence-based practices to improve children’s mental health in schools. However, some studies also suggest that mindfulness programs do not have added values compared to other mental health promotion interventions. These differences in effectiveness can partly be due to the lack of...

The Effectiveness of Virtual Reality–Based Mindfulness Interventions for Managing Stress, Anxiety, and Depression: Protocol for a Systematic Review and Meta-Analysis of Randomized Controlled Trials (Preprint)

Ravi Shankar, Anjali Bundele, Amartya Mukhopadhyay

BACKGROUND While traditional mindfulness-based interventions demonstrate effectiveness in improving mental health outcomes, their delivery methods face significant challenges related to accessibility and engagement. Geographic barriers to trained facilitators, time constraints for in-person sessions, and participant dropout rates of 15% to 30% due to perceived monotony limit intervention reach...

Feasibility of Modified Mindfulness Training Program on Antenatal Depression and Perceived Stress Among Expected Mothers with Male Child Preference

. Badil, Najma Naz, Dildar Muhammad et al. preprint

Background and Objectives: Antenatal depression and perceived stress are prevalent mental health challenges in pregnant women, associated with male-child preference. The study aimed to assess the feasibility of a modified mindfulness training program on antenatal depression and perceived stress levels among expected mothers with male child preference at a public sector tertiary care hospital in...

The Mediating Effects of Thought Suppression, Emotion Suppression, and Self-Esteem on the Relationship between Mindfulness and Depression in Youth: A Cross-Sectional Study

Xuanyi Wang, Shulin Chen preprint

AbstractBackground Youths are particularly susceptible to depression, as they face a critical but vulnerable phase of cognitive development. Cognitive interventions for youth depression are therefore warranted. Mindfulness, considered as the third wave of the cognitive revolution, shows great potential to address risk factors of depression, especially suppression and low self-esteem. Therefore,...

Mindfulness-Based Cognitive Behavioral Intervention as a Preventative Approach for Elderly Individuals at Risk of Depression and Anxiety: A Randomized Controlled Trial

Rachna Garg, Shubhagata Awasthi, Naveen Gupta preprint

Abstract Background: Mental health challenges, particularly depression and anxiety, are increasingly prevalent among the elderly, highlighting a need for preventative strategies. Mindfulness-Based Cognitive Behavioral Intervention (MBCBI) combines mindfulness techniques with cognitive restructuring to enhance emotional regulation and resilience in older adults. This pilot study examines the...

Examining What Works for Whom and How in Mindfulness-Based Cognitive Therapy (MBCT) for Recurrent Depression: A Moderated-Mediation Analysis in the PREVENT Trial (in press)

Jesus Montero-Marin, Verena Hinze, Shannon Maloney et al. preprint

Background: Personalized management of recurrent depression, considering individual patient characteristics, is crucial. Aims: This study evaluates the potentially different mediating role of mindfulness skills in managing recurrent depression using mindfulness-based cognitive therapy (MBCT) among patients with varying depression severity. Method: Data from the PREVENT trial, comparing MBCT...

Dynamic Mechanisms and Efficacy of Online Mindfulness-Based Cognitive Therapy for Current Depression: A Randomized Controlled Trial Using Network Intervention Analysis

Mingyang Zhou, Jingyi Jiang, Zenan Liu et al. preprint

Background: Mindfulness-Based Cognitive Therapy (MBCT) has demonstrated efficacy in preventing depression relapse and alleviating residual symptoms. However, evidence for its effectiveness in patients currently experiencing depressive episodes—particularly when delivered online—remains limited. This study evaluated the therapeutic effects and dynamic symptom-level mechanisms of online MBCT in...

The Role of Mindfulness-Based Stress Reduction in Alleviating Depression, Enhancing Coping Skills, and Promoting Workplace Satisfaction and Well-Being Among Nurses: A Systematic Review (Preprint)

Wesam Al-Magharbeh, Khaldoon Ayed Alnawafleh, Hazem AbdulKareem Alfanash

BACKGROUND Stress is rampant in nursing because of the demanding nature of the profession. For many nurses, their work environments are highly stressful with long working hours and a lot of emotional demands predisposing them to the risk of mental health problems, burnout, psychological distress, and reduced job satisfaction. For many nurses, coping with such stressful environments can be...

Intravenous ketamine is ineffective compared to midazolam for treatment-resistant depression: a double-blind, randomized controlled study

Keerati Pattanaseri, Juthawadee Lortrakul, Kankamol Jaisin et al. preprint

Abstract Background: Studies have confirmed the rapid antidepressant action of ketamine in depressive episodes. Nevertheless, a standardized procedure for the delivery of ketamine infusion in individuals suffering from treatment-resistant depression, particularly in terms of infusion frequency and total dosage, remains undetermined. In addition, an efficacious ketamine regimen for persistent...

Randomized Placebo-Controlled Phase 2 Study of Extended-Release Ketamine Tablets (R-107) for Treatment-Resistant Depression – the BEDROC Study

Paul Glue, Colleen Loo, Johnson Fam et al. preprint

Abstract Ketamine has rapid-onset antidepressant activity in patients with treatment-resistant major depression (TRD). The safety and tolerability of racemic ketamine may be improved if given orally, as an extended release tablet (R-107), compared with other routes of administration. In this phase 2 multicentre clinical trial, adult patients with TRD and Montgomery-Asberg Depression Rating...