Communications Biology
July 3, 2026
Fengkai He, Xiaojun Xu, Y Y Zhu et al.
Depression involves dysregulation across distributed cortico-limbic circuits, and ketamine is notable for its rapid antidepressant effects. Although depression and ketamine treatment have been linked to altered brain network topology, how within-frequency and cross-frequency coupling are jointly reorganized at the brain-wide level remains unclear. Here, we developed a frequency-varying...
bioRxiv (Cold Spring Harbor Laboratory)
July 3, 2026
Sébastien Czajko, Jelle Zorn, Oussama Abdoun et al.
preprint
Nonduality is a foundational but conceptually elusive notion across several contemplative traditions. Nondual traditions challenge the assumption that a subject-object structure characteristic of ordinary experience is an intrinsic feature of conscious awareness. However, little remains known about the neurocognitive mechanisms associated with such experiential state. Here, we investigated how...
Neuroimage
July 1, 2026
Yan Zhang, Xiarong Li, Zhenlan Jin et al.
Persistent debate surrounds whether the frontal lobe supports the emergence or reporting of consciousness, raising the hypothesis that distinct frontal subregions may support these processes. We addressed this by combining electroencephalography (EEG) with eye-tracking in Report and No-Report paradigms. Eye-movement features distinguished conscious and unconscious trials in the no-report task....
bioRxiv (Cold Spring Harbor Laboratory)
June 16, 2026
Paulina Clara Dagnino, Irene Acero-Pousa, Gorka Zamora-López et al.
1 citation
preprint
Abstract In recent decades, the psychedelic psilocybin has been studied as a potential treatment for major depressive disorder (MDD), offering an alternative to traditional antidepressants. However, the brain changes underlying the clinical effects of different interventions remain unclear. Here, we investigated the effects of psilocybin and a conventional antidepressant, escitalopram, from the...
Zenodo (CERN European Organization for Nuclear Research)
June 15, 2026
Tenzin Trepp
preprint
We examine the claim that a minimal-conceptual, “bare” awareness underlies ordinary experience, and whether this pre-conceptual awareness (PCA, or minimal-dual awareness) should be understood primarily as an earlier, biologically rooted developmental baseline, or as a disclosure of a deeper ontological reality. The Retrieval hypothesis treats PCA as a cognitive–neural default mode that can be...
bioRxiv (Cold Spring Harbor Laboratory)
June 12, 2026
Nikola Jajcay, Čestmír Vejmola, Jakub Korčák et al.
preprint
Abstract Psilocybin and other serotonergic psychedelics show therapeutic promise for psychiatric disorders, yet objective neural correlates linking the acute psychedelic state to persisting psychological outcomes remain limited. Electroencephalography (EEG) microstate analysis characterizes the rapid spatiotemporal organization of large-scale brain activity, offering a millisecond-resolution...
Frontiers in Systems Neuroscience
June 4, 2026
Elena Bondi, Flavia Carbone, Giandomenico Schiena et al.
Introduction: Affective disorders (ADs) are characterized by profound emotional processing deficits involving disrupted neural network activity and connectivity, particularly within the default mode network and fronto-temporal circuits, with abnormalities in theta and alpha oscillatory patterns. While current treatments primarily target mood symptoms, emotional processing impairments often...
Psychophysiology
June 1, 2026
Tongxin Liu, Sonja A. Kotz, Antonio Criscuolo et al.
1 citation
Spontaneous pupil fluctuations (SPFs) during rest provide a non-invasive, low-cost index of central arousal dynamics, independent of cognitive task demands. These features position SPFs as promising markers for baseline neurophysiological activity in both basic and translational research. This review synthesizes current evidence on the resting-state pupil-brain system, focusing on its core...
Zenodo (CERN European Organization for Nuclear Research)
May 26, 2026
Thyagarajan Shivashanmugam, Anish Mehta
preprint
Meditation research is frequently framed in terms of reduced self-referential processing, yet converging evidence suggests that this description encompasses multiple mechanistically distinct states. The present work proposes a specific subclass, termed tranquil states, defined as resting-state conditions characterized by concurrent attenuation of default mode network activity — a finding...
Journal Of Social Research
May 22, 2026
Retno Ryani Kusumawati, Akhmad Baidun, Dery Kurniawan et al.
This research aims to explore and analyze the relationship between neuroscience and creative processes in order to gain a more comprehensive understanding of the neural mechanisms underlying human creativity. The method used was qualitative research with a descriptive approach through literature studies, with data collection techniques in the form of searching scientific literature from journal...