Zenodo (CERN European Organization for Nuclear Research)
January 26, 2026
Fernando Mora López, Johynny Solís Solís, Ekaterina Daniela Hernández Baker et al.
preprint
This review examines the therapeutic efficacy of psilocybin for major depressive disorder by integrating findings from clinical trials, meta-analyses, and mechanistic research. A comprehensive literature search across major scientific databases identified empirical studies evaluating psilocybin’s effects on depressive symptomatology, safety, and underlying neurobiological mechanisms....
International Journal of Innovative Technologies in Social Science
January 23, 2026
Jakub Klepacz, Radosław Swędrak, Marzena Swojnóg et al.
The escalating global burden of mental health disorders, coupled with the stagnation of innovation in traditional monoaminergic pharmacotherapy (e.g., SSRIs), has precipitated a critical need for novel therapeutic paradigms. This article presents a comprehensive systematic review of the so-called "Psychedelic Renaissance," focusing on the clinical resurgence of classical serotonergic...
January 9, 2026
Valerie van Mulukom
preprint
This article proposes a dual-self states framework to demonstrate how phenomenology and neuroscience of embodied and altered states of consciousness illuminate the nature of consciousness and the sense of self. It argues that consciousness is best conceived as dynamic configurations of a reflective and an experiential self state, rather than as static, taxonomic layers of self. The reflective...
2026
Femi Oyebode
Abstract The term ‘self’ refers to a dynamic and evolving concept that is contrasted with our awareness of physical objects in the world and as such is the centre and focus of our internal experiences, as an awareness of ourselves as a centre of experience. This chapter deals with the philosophical accounts of John Locke, David Hume, Immanuel Kant and Derek Parfit. These varying accounts...
Frontiers in Psychiatry
2026
Sonora Yun, Martijn Figee
Treatment-resistant depression (TRD) poses a significant challenge, with many patients failing to achieve remission with conventional therapies. While repetitive Transcranial Magnetic Stimulation (rTMS) is an established and effective neuromodulatory treatment for TRD, a notable proportion of patients do not fully respond. Despite the clinical utility of rTMS, response variability remains a...
Imaging Neuroscience
2026
Tiara Bounyarith, David Braun, Aaron Kucyi
Much of a typical individual's mental life is characterized by spontaneous thoughts that occur independently of external stimuli. In prior studies, ongoing mental experiences and their neural correlates have been captured using thought probes presented at random intervals during functional magnetic resonance imaging (fMRI). However, this approach results in temporally imprecise estimates of...
Frontiers in Neuroscience
2026
Misuzu Oishi, Kei Sasaki, Noriko Sakurai et al.
Autonomous sensory meridian response (ASMR) is a tingling sensation that originates in the occipital region and spreads along the neck and spine, elicited by specific audiovisual stimuli known as ASMR triggers. The characteristics of ASMR-related changes in brain activity relative to other external stimuli, and whether these changes are specific to ASMR, remain unclear. The aim of this study is...
Journal of Cognitive Neuroscience
2026
Vasil Kolev, Kosio Beshkov, Peter Malinowski et al.
2 citations
The present study applied spectral Granger causality (GC) analysis to EEG recordings obtained during focused attention meditation (FAM), open monitoring meditation (OMM), and loving kindness meditation (LKM) in highly experienced meditators. The aim of the investigation was to characterize distinct connectivity signatures associated with each meditation style by examining the strength,...
Open Mind
2026
Thyagarajan Shivashanmugam, Anish Mehta
preprint
This component develops a constraint-based framework for the empirical specification of tranquil states in meditation research. The manuscript proposes that tranquil states are characterized by the co-attenuation of default mode network activity and salience-network baseline drive, while distinguishing this configuration from broader trait effects, altered states, or generalized reductions in...
Frontiers in Human Neuroscience
2026
Josh Roeloffs, Jack A Tuszynski
Dual-process theory of the brain distinguishes fast, parallel, late-commitment cognition (System 1) from slow, sequential, early-commitment cognition (System 2), yet lacks a mechanistic explanation for how these modes operate or how the brain switches between them. Quantum cognition research demonstrates that human decision-making follows quantum probability models under low confidence and...