Objectives: We investigate the relationship between the loss of consciousness (LOC) and the state of default mode network (DMN) connectivity in diffuse axonal injury (DAI) patients, using diffusion tensor tractography (DTT). Methods: Twenty-one consecutive patients with DAI were recruited in this study. The DMN connectivity [medial prefrontal cortex (mPFC)—posterior cingulate cortex...
Objective This study investigated the macroscopic neural mechanisms of cognitive impairment after Deep Nuclei Intracerebral Hemorrhage (DNICH) from the dimensions of brain activity and brain networks, and further identified characteristic fingerprints of cognitive representation. Method Patients with cognitive impairment after DNICH and healthy controls (HC) were prospectively and consecutively...
Testosterone exerts widespread effects on brain structure and function, yet its influence on large-scale neural networks, particularly the default mode network (DMN), remains poorly understood. The role of the DMN in self-referential processing, social cognition, and mood regulation has been demonstrated over the last decade. Neuroimaging studies suggest a link between testosterone and...
Water-based contemplative and recovery practices — from head-out immersion and cold-water bathing to floatation-based sensory reduction — are consistently associated with shifts in autonomic and, increasingly, brainnetwork activity. This paper synthesizes the physiological literature on hydrostatic, thermal, vestibular, and sensory-attenuation effects of water immersion and evaluates the...
Background: Posterior α suppression, frontal θ enhancement and fronto-posterior α-band coupling are routinely interpreted together as an 'EEG-DMN-like' rest-to-task marker. Whether they replicate as a unitary pattern or dissociate across metric families, task windows and cognitive paradigms remains insufficiently characterised within a single harmonised pipeline. Methods: ds004148 (n = 60;...
Background Accelerated resting-state fMRI (rs-fMRI) may reduce scan time and participant burden, but whether shortened acquisitions preserve functional connectivity profiles and clinical associations remains unclear. This study compared hyperband and conventional acquisitions in characterizing default mode network (DMN) connectivity and associations with substance use. Methods A community...
Repetitive transcranial magnetic stimulation (rTMS) has been explored as an intervention in typical amnestic Alzheimer's Disease (AD). However, its effects on episodic and associative memory in atypical forms of AD are less known. Posterior cortical atrophy (PCA) is primarily characterized by visuospatial and visuoperceptual symptoms, although significant episodic memory deficits are often...
Objective Dysfunction of the default mode network (DMN) is strongly linked to pain processing, as well as onset and progression of chronic pain disorders; however, its specific role in the pathogenesis of tension-type headache (TTH) remains incompletely understood. This study aims to explore the network homogeneity (NH) of the DMN in the pathophysiological mechanisms underlying TTH. Methods...