Journal of Affective Disorders
January 15, 2021
Dakota Mauzay, Emily M LaFrance, Carrie Cuttler
Little is known about the the acute effects of cannabis on symptoms of OCD in humans. Therefore, this study sought to: 1) examine whether symptoms of OCD are significantly reduced after inhaling cannabis, 2) examine predictors (gender, dose, cannabis constituents, time) of these symptom changes and 3) explore potential long-term consequences of repeatedly using cannabis to self-medicate for OCD...
Journal of Psychedelic Studies
January 15, 2021
Mark S. Ferrara
24 citations
AbstractThis paper demonstrates that cannabis can evoke “peak-experiences”—the name psychologist Abraham Maslow gave to fleeting moments of expanded perception indicative of self-transcendence—when used alongside more traditional religious practices such as meditation, fasting, contemplative prayer, and sacramental ritual. For that reason, religious seekers around the globe have deployed...
Progress in Neuro-Psychopharmacology and Biological Psychiatry
January 10, 2021
Hanna J Szkudlarek, Mar Rodríguez-ruiz, Roger Hudson et al.
Clinical and pre-clinical evidence demonstrates divergent psychotropic effects of THC vs. CBD. While THC can induce perceptual distortions and anxiogenic effects, CBD displays antipsychotic and anxiolytic properties. A key brain region responsible for regulation of cognition and affect, the medial prefrontal cortex (PFC), is strongly modulated by cannabinoids, suggesting that these dissociable...
Schizophrenia Research
January 9, 2021
Leah G. Pope, M. Manseau, M. Kelley et al.
OBJECTIVE The nature of associations between recent cannabis use and negative symptoms, positive symptoms, and neurocognitive deficits remains unclear. In a relatively large sample of well-characterized patients with first-episode psychosis, we hypothesized that, compared to first-episode patients without cannabis use in the three months prior to first hospitalization, those having used...
Journal of Psychopharmacology
January 9, 2021
Abigail M. Freeman, Claire Mokrysz, Chandni Hindocha et al.
6 citations
BACKGROUND: While the acute effects of cannabis are relatively benign for most users, some individuals experience significant adverse effects. This study aimed to identify whether variation in schizotypal personality traits and frequency of cannabis use influence the acute effects of delta-9-tetrahydrocannabinol (THC). METHODS: Individual participant data from four double-blind, randomised,...
Libro Comunicaciones
2021
4-bromo-2,5-dimetoxifeniletilamina, también conocido como 2C-B, "tussi", "nexus" o "cocaína rosa" es una droga sintética del grupo de las feniletilaminas, con efectos alucinógenos y euforizantes, debido a su efecto como agoniza parcial de receptores 5HT-2A, 5HT-2B y 5HT-2C, cuyo consumo se ha extendido en los últimos años. Presentamos el caso de una paciente de 22 años sin antecedentes...
Libro Comunicaciones
2021
Maitane Oscoz-Irurozqui, Maria Guardiola-Ripoll, Carmen Almodóvar-Payá et al.
1. Objectives: While endocannabinoid system seems to be involved in processes underlying psychosis, research about Cannabinoid Receptor 2 gene (CNR2) is scarce and inconclusive. Some few reports indicate that CNR2 plays a role in psychiatric conditions, including depression or drug addiction (Onaivi et al., 2009). We aimed to evaluate the role of CNR2 and its interplay with cannabis on...
Frontiers in Neuroscience
2021
Christian D Richard, Jared R Poole, Marissa McConnell et al.
The trend toward cannabis legalization in the United States over the past two decades has unsurprisingly been accompanied by an increase in the number of cannabis users and use patterns that potentially pose wider risks to the public like driving under the influence. As such, it is becoming increasingly important to develop methods to accurately quantify cannabis intoxication and its associated...
Brazilian Journal of Health Review
2021
Marina Bertoldo Baeza, Ricardo S. S. Durães, Antonio de Pádua Serafim
Background: Studies have pointed out the increased risk of developing psychosis in adulthood related to cannabis use during adolescence.Aim: To conduct a systematic review of the literature on the use of cannabis in adolescence and risk of psychosis.Method: We conducted a systematic review in accordance with PRISMA guidelines.We searched by PubMed, PsycINFO, and SciELO database between 2010 and...
Archives of Clinical and Medical Case Reports
2021
Zoe Boulot, F. Gabayet, Mathieu Besnard et al.
We describe a young male patient who questions his diagnosis of schizophrenia made 10 years ago, and whose clinical presentation and history seem in favour of cannabisinduced psychotic episodes. This case questions the risk of a hasty diagnosis when it comes to concomitant psychosis and cannabis use. This presentation raises medical, therapeutical, and ethical questions. With cannabis use...