Cannabis use during adolescence is associated with an increased risk of developing psychosis. According to a current hypothesis, this results from detrimental effects of early cannabis use on brain maturation during this vulnerable period. However, studies investigating the interaction between early cannabis use and brain structural alterations hitherto reported inconclusive findings. We...
March 1, 2021Benjamin J. Warnick, Alexander S. Kier, Emily M LaFrance et al.
Abstract New venture ideation is critical to the entrepreneurial process. To generate creative ideas, some entrepreneurs turn to cannabis, proposing its benefits. However, extant research has not validated such claims. Using a new venture ideation task, we explore differences between cannabis users' and non-users' creativity in new venture ideation by assessing the originality and feasibility...
ABSTRACT: Individuals with first episode psychosis (FEP) use cannabis at high rates. A family-based intervention grounded in motivational interviewing (MI) appears promising. Focus groups ( N = 3) were conducted with family members ( n = 8) of individuals with FEP. Questions were developed based on theory of planned behavior (TPB) to identify factors contributing to intentions to utilize MI to...
Substance AbuseFebruary 22, 2021S. Kiburi, K. Molebatsi, Vuyokazi Ntlantsana et al.
Background Previous research has reported increased risk for psychosis among individuals who use cannabis during adolescence. We conducted a systematic review and meta-analysis to investigate the interaction between adolescent cannabis use and other factors in moderating risk for psychosis later in life. Method We searched four electronic databases in June 2020 for articles that assessed...
Background: Cannabis is known to have a broad range of effects on behavior, including experiencing a “high” and tranquility/relaxation. However, there are several adverse behavioral sequalae that can arise from cannabis use, depending on frequency of use, potency (e.g., THC content), age of onset, and cumulative exposure. This systematic review examined evidence for cannabis-related adverse...
Background: Few studies have examined how Δ9-Tetrahydrocannabinol (THC), the main psychoactive component of cannabis, impacts brain reward circuitry in humans. In this study, we examined if an acute dose of THC altered resting state functional connectivity between the striatum and prefrontal cortex among healthy young adults with limited cannabis use. Methods: Participants received THC (n=24)...
Perinatal exposure to Δ9-tetrahydrocannabinol (THC) affects brain development and might increase the incidence of psychopathology later in life, which seems to be related to a dysregulation of endocannabinoid and/or dopaminergic systems. We here evaluated the transcriptional regulation of the genes encoding for the cannabinoid CB1 receptor (Cnr1) and the dopamine D2 receptor (Drd2) in perinatal...
Objective: To determine the frequency and correlates of cannabis use among the psychiatric inpatients presenting with first episode of psychosis at Combined Military Hospital (CMH), Lahore. Study Design: Correlational study. Place and Duration of Study: Combined Military Hospital Lahore, from Nov 2016 to Apr 2017. Methodology: A total of 88 patients between 18-40 years of age, both male and...
The increasing legal availability of cannabis has important implications for road safety. This systematic review characterised the acute effects of Δ9-THC on driving performance and driving-related cognitive skills, with a particular focus on the duration of Δ9-THC-induced impairment. Eighty publications and 1534 outcomes were reviewed. Several measures of driving performance and...