The Brown University Child & Adolescent Psychopharmacology Update
June 25, 2025
Alison Knopf
Researchers looked at a common alteration in the dopamine system to investigate the mechanism possibly linking cannabis use and schizophrenia.
Medical Cannabis and Cannabinoids
June 25, 2025
Lakshmi Kumar, Tory R Spindle, C. Austin Zamarripa et al.
Introduction: Cannabis contains hundreds of chemical constituents beyond delta-9-tetrahydrocannabinol (Δ9-THC), which is thought to be the primary driver of most of its acute pharmacodynamic effects. The entourage effect theory asserts that the pharmacological and therapeutic effects of cannabis are not solely attributable to Δ9-THC but are influenced by other constituents, such as minor...
European Archives of Psychiatry and Clinical Neuroscience
June 23, 2025
Vicente Molina, Alvaro Diez, Inés Fernández-Linsenbarth et al.
Cannabis use is highly prevalent in individuals with psychosis, raising concerns about its influence on brain function. Electroencephalography (EEG) studies have identified alterations in brain activity in psychosis, including changes in spectral entropy (SE) modulation and connectivity strength (CS). However, the degree to which cannabis use contributes to these alterations remains unclear....
Journal of Psychiatric Research
June 19, 2025
Valerio Ricci, Ilenia di Muzio, Mancusi Gianluca et al.
2 citations
AIMS: This study aimed to investigate the differences in psychotic symptomatology, dissociative symptoms, alexithymia, and aberrant salience among three groups: non-cannabis users (NU), natural cannabis users (NC), and synthetic cannabinoid users (SCs). The study also explored the patterns of alexithymia and its associations with other psychopathological dimensions in these populations....
BRILL eBooks
June 16, 2025
Bonnie Glass‐coffin, Saundra Shanti
This chapter describes the traditions, training, alterations of consciousness, healing ritual, and ethnomedical ideologies of Cannabis sativa, which is the oldest, most widely used, yet least considered plant teacher of the psychedelic renaissance. After briefly summarizing the recent literature about the deeply intertwined histories of Cannabis sativa and its intimate relationship with human...
Journal of dual diagnosis
June 16, 2025
Amar Ghelani
Abstract Objective Cannabis use contributes to negative psychosocial outcomes among youth in Early Psychosis Intervention (EPI) programs and families are crucial to recovery. This study sought to understand how youth in EPI programs perceive their families to influence their cannabis use and how cannabis affects family relationships. Methods A qualitative approach and thematic analysis were...
June 16, 2025
Anna Waldstein, Caley Cannon
Rastafari is a Pan-African spiritual, socio-political, and ecological movement that uses the Herb (Cannabis spp.) as an entheogenic agent for decolonizing consciousness to promote well-being. The movement counters the centuries of injustice and oppression perpetrated through the trans-Atlantic slave trade with a power derived from links to African livity, a core spiritual lifestyle that...
Alcoholism & Drug Abuse Weekly
June 2, 2025
Alison Knopf
In a small study, researchers observed a possible link based on magnetic resonance imaging (MRI) between elevated dopamine function, cannabis use, and schizophrenia. It is known that cannabis use is linked to psychosis, and dopamine is linked to psychosis, but whether there is a dopamine link is unclear.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
June 2025
Gianluca Lavanco, Valentina Castelli, Cesare D'Amico et al.
Mitochondria are central to cellular energy metabolism, contributing to synaptic transmission and plasticity. The mitochondrial membranes present the cannabinoid type-1 receptor (mito-CB1R), which has been functionally linked to neuronal energy supply and cognitive processing. Prenatal exposure to Δ9-tetrahydrocannabinol (pTHC) has been associated with cognitive impairments associated with...
Smart health
June 1, 2025
Honglu Li, Bin Han, Cong Shi et al.
Cannabis use has become increasingly prevalent due to evolving legal and societal attitudes, raising concerns about its influence on public safety, particularly in driving. Existing studies mostly rely on simulators or specialized equipment, which do not capture the complexities of real-world driving and pose cost and scalability issues. In this paper, we investigate the effects of cannabis on...