Pharmacology, Biochemistry, and Behavior
December 1, 2024
Lifen Liu, Rui Li, Lanxia Wu et al.
3 citations
Patients diagnosed with post-traumatic stress disorder (PTSD) mainly exhibit enduring adverse emotions, heightening susceptibility to suicidal thoughts and behaviors. Notably, metabolites of ketamine, particularly (2R,6R)-hydroxyketamine (HNK), have demonstrated favorable antidepressant properties. However, the precise mechanism through which HNK exerts its therapeutic effects on negative...
Asian Journal of Psychiatry
December 1, 2024
Hitesh Kumar Behera, Ramesh Joga, Sravani Yerram et al.
Psychedelic drug therapy has gained prominence for its potential in treating various mental health conditions, including depression, post-traumatic stress disorder (PTSD), and anxiety. Psychedelic treatment differs from conventional psychiatric approaches in mode of action, legal status, and treatment approach. This work delves into the therapeutic potential, mechanisms, and regulatory...
Health Education & Behavior
December 1, 2024
Ilana Berlowitz, Ernesto García Torres, Juan Celidonio Ruiz Macedo et al.
3 citations
Although the tobacco plant has been employed as a medicinal and sacred herb by Indigenous cultures across the Americas, its usage drastically changed after the 15th-century colonial arrival; its large-scale commodification and global marketing once brought to Europe lead to hedonic and addictive uses harmful to health. As a consequence, tobacco smoking is now one of the largest public health...
Journal of Student Research
November 30, 2024
Arman Fard, Amy N. Cohen
Psychedelics are emerging as an effective way to combat mental health disorders such as anxiety, depression, PTSD, and substance abuse. Psychedelics such as psilocybin can decrease overactivity in regions of the brain that are associated with anxiety and depression; for instance, psilocybin acts as an agonist on brain receptors to induce consciousness-altering neural responses. Compared to...
The International Journal of Neuropsychopharmacology
November 29, 2024
Helen M Collins
18 citations
Abstract Psychedelics are emerging as potential treatments for a range of mental health conditions, including anxiety and depression, treatment-resistant depression, and substance use disorders. Recent studies have also suggested that the psychedelic psilocybin may be able to treat obsessive–compulsive disorder (OCD). Since the 1960s, case studies have reported improvements to obsessive and...
medRxiv Preprint Server
November 26, 2024
Bonnie L. Quigley, Adem T. Can, Megan Dutton et al.
1 citation
preprint
Ketamine is being actively investigated as a rapid-acting treatment for many conditions with a stress-related psychopathology, including post-traumatic stress disorder (PTSD). The majority of studies regarding ketamine treatment for PTSD to date (including open-label and randomised control trials) have focused on intravenous (IV) ketamine administration. This administration route has...
Jurnal Penelitian Pendidikan IPA
November 25, 2024
Letti Kumajas, Shanti Wardhaningsih
The increasing workload, attributed to a high number of patients and limited human resources, is a major cause of stress among nurses. This stress can lead to burnout syndrome, characterized by emotional exhaustion, depersonalization, and a decrease in personal accomplishment, ultimately affecting the quality of nursing care provided to patients. Instances of nurse stress are not confined to a...
British Journal of Clinical Pharmacology
November 25, 2024
Aaron Klaiber, Mélusine Humbert‐droz, Laura Ley et al.
6 citations
Psychedelics, including mescaline, may serve as novel treatments for depression and anxiety. However, data is scarce on the safety of mescaline. The present pooled analysis included two double-blind, randomized, placebo-controlled studies with a total of 48 participants and 96 mescaline administrations. Single oral-dose administrations (n = 16/dose) of mescaline at doses of 100-800 mg were...
Medical Science Monitor
November 24, 2024
Xuelian Wang, Yinzhong Lu, Chunhong Gu et al.
3 citations
BACKGROUND The study aims to explored the impact of short-term mindfulness meditation training on physiological and psychological stress levels in patients with gastrointestinal tumors during the perioperative period. MATERIAL AND METHODS We randomly allocated 78 participants to either the experimental group (n=39) or the control group (n=39). The control group received perioperative nursing,...
Journal of Psychoactive Drugs
November 22, 2024
Wesley C Ryan, Boris D. Heifets
2 citations
The use of ketamine and ketamine-assisted psychotherapy (KAP) for treatment of depression has grown dramatically, though much of these data are short term. The clinical profile of maintenance treatment remains poorly characterized. We assessed maintenance KAP for efficacy, tolerability, and reasons for dropout. This observational study retrospectively analyzed electronic health records from an...