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Alexandre Lehmann

8 papers in the library · 66 citations · publishing 2023-2026

Papers

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Patterns of Psychedelic Use in Italy: Insights from the Global Psychedelic Survey

Clinical Neuropsychopharmacology and Addiction September 1, 2026 Beatrice Dal Bianco, Matteo Buonarroti, Alessandro Lo Jacono et al.

Background: Epidemiological data on psychedelic use in Italy is limited. In this study, Italian responders in the Global Psychedelic Survey 2025 were subanalyzed to describe patterns of use, motivations, subjective experiences, and health correlates. Methods: Adults (≥21 years) with lifetime psychedelic exposure, residing in or born in Italy or San Marino, were surveyed in a web-based,...

Evaluating the Combined Effects of Cannabinoids and Music, and Their Interactions in Mood and Emotional Regulation: An Online Survey.

Cannabis and Cannabinoid Research July 8, 2026 Olivier Valentin, Benjamin R Zendel, Philippe Fournier et al.

While both cannabis and music have demonstrated significant independent impacts on emotional states, the synergies between these two modalities remain underexplored. This study investigates the interactions between cannabis consumption and music listening, focusing on their effects on emotional experiences, mood regulation, and sensory perceptions. An online cross-sectional survey consisting of...

The rhythms of trance: Cultural phenomenology and neural mechanisms of music-induced non-ordinary states of consciousness.

Neuroscience and Biobehavioral Reviews July 1, 2026 Athanasia Kontouli, Michael J Hove, Alexandre Lehmann et al.

This review integrates anthropological and neuroscientific perspectives to elucidate music-induced trance processes and their relevance to non-ordinary states of consciousness (NSCs). The objectives are to deepen the understanding of trance phenomena, delineate links across diverse trance expressions, and inform future neuroscientific research. Drawing on anthropological insights, we examine...

An international Delphi consensus for reporting of setting in psychedelic clinical trials.

Nature Medicine June 3, 2025 Chloé Pronovost-Morgan, Kyle T. Greenway, Leor Roseman et al. 26 citations

Psychedelic substances exhibit complex interactions with the 'set and setting' of use, that is, the mental state of the user and the environment in which a psychedelic experience takes place. Despite these contextual variables' known importance, psychedelic research has lacked methodological rigor in reporting extra-pharmacological factors. This study aimed to generate consensus-based...

Music and non-music approaches in psilocybin-assisted psychotherapy: The sound of silence

Journal of Psychedelic Studies May 15, 2025 Sara G. Gloeckler, Julien Thibault Lévesque, Alexandre Lehmann et al. 3 citations

Abstract Music is integral to Psilocybin-assisted psychotherapy (PAP), believed to enhance therapeutic outcomes by structuring experiences and facilitating emotional expression. However, the effects of conducting PAP without music are underexplored. This study examines the experiences of two breast cancer patients undergoing psilocybin therapy under Canada's compassionate access program,...

Preferences and Attitudes Toward Music in Nonclinical Uses of Psychedelics.

Psychedelic Med (New Rochelle) December 2, 2024 Sara G. Gloeckler, Alexandre Lehmann, Sara de la Salle et al. 4 citations

Background: The resurgent interest in psychedelic-assisted therapy for conditions like depression, end-of-life anxiety, and post-traumatic stress disorder is generating highly promising results. Within this therapeutic context, music's role is multifaceted, seen as a critical environmental component and even akin to a hidden therapist. Contemporary clinical protocols often advocate for music...

Psilocybin prevents habituation to familiar stimuli and preserves sensitivity to sound following repeated stimulation in mouse primary auditory cortex

bioRxiv (Cold Spring Harbor Laboratory) September 30, 2024 Conor P. Lane, Veronica Tarka, Olivier Valentin et al. 1 citation preprint

Abstract Psilocybin, a psychoactive substance derived from fungi, has been utilized historically by diverse cultures for both medicinal and non-medicinal purposes, owing to its ability to elicit profound sensory and cognitive alterations and sustain long-term changes in mood and cognition. Promising results from recent clinical studies have generated a wave of interest in employing psilocybin...

The Montreal model: an integrative biomedical-psychedelic approach to ketamine for severe treatment-resistant depression

Frontiers in Psychiatry September 19, 2023 Nicolas Garel, Jessica Drury, Julien Thibault Lévesque et al. 32 citations

Background Subanesthetic ketamine has accumulated meta-analytic evidence for rapid antidepressant effects in treatment-resistant depression (TRD), resulting in both excitement and debate. Many unanswered questions surround ketamine’s mechanisms of action and its integration into real-world psychiatric care, resulting in diverse utilizations that variously resemble electroconvulsive therapy,...