Neurobiology of StressMay 1, 2025Alanna Kit, Kate Conway, Savannah Makarowski et al.5 citations
There is growing interest in exploring the therapeutic potential and mechanisms of action of psilocybin on stress-related neuropsychiatric disorders, including depression, generalized anxiety disorder (GAD), post-traumatic stress disorder (PTSD), obsessive-compulsive disorder (OCD), addiction, and disordered eating. Despite promising progressions in preclinical and clinical research, the...
The purpose of the study was to describe the benefits and harm of using psychedelics in the treatment of patients with mental health and substance abuse disorders. The study focused on classic psychedelics, specifically psilocybin and LSD. The study was carried out as an integrative literature review and the data was sought using Medic, Cinahl, PubMed MEDLINE and PsycINFO databases. A total of...
Female prisoners in Latin America experience significantly higher rates of mental health issues compared to their male counterparts. The most prevalent include anxiety and stress, which stem from feelings of insecurity, perceived failure, long periods of detention, and the inability to care for their children. Furthermore, over 50% of female prisoners have been exposed to traumatic events,...
PharmaceuticalsApril 30, 2025Paola Bozzatello, Roberta Novelli, Rebecca Schisano et al.6 citations
Psychiatric disorders are a major cause of illness in the world. Unfortunately, many patients are resistant to treatment and present serious complications. Schizophrenia is refractory to treatment in about one-third of patients. Antidepressants are effective in about half of patients. Suicidal ideation is an increasing issue in patients with mixed features in bipolar disorder (BD). Therefore,...
It is still unknown how current trends in psychedelic use among adolescents are related to mental health. This study reports on the prevalence of psychedelic use in a Swedish representative nationwide drug survey and its association with mental health outcomes and user personality. A cross-sectional study using data from the latest 2024 Swedish Council for Information on Alcohol and Other Drugs...
The pharmaceutical industry in India is undergoing significant expansion, with Medical Sales Representatives (MR) playing an integral role in promoting pharmaceutical products and facilitating communication between healthcare providers and the industry. However, the demanding nature of this profession often results in elevated levels of psychological strain, including stress, anxiety, and...
Psychedelic experiences involving extreme feelings of horror, helplessness, and perceived threats can be traumatizing. Traumatic psychedelic experiences are a rare, extreme, and largely preventable form of challenging experience which can arise due to frightening psychedelic drug effects, unsafe settings, and emergence of pre-existing trauma. Some people recover quickly, but others develop...
High prevalences of anxiety and depression have been found in those with COPD which can exacerbate physically related impacts of increased levels of disability, and reduced enjoyment of life. Of particular concern is the anxiety-breathlessness cycle and reduced self-efficacy, which both adversely affect self-management of symptoms. Recognition of the need to address these issues has led to use...
This chapter provides an overview of what individuals may encounter during a psychedelic journey, emphasizing that each experience is unique and influenced by factors such as mindset, environment, dosage, and the type of psychedelic used. Common experiences include vivid visual effects, enhanced sensory perception, feelings of euphoria, ego dissolution, introspection, emotional release, and...
Introduction: High-dose psilocybin has shown potential in treating various psychiatric disorders, but its perceptual and cognitive effects, along with the risk of adverse events, highlight the need for alternative treatment approaches. One such approach is the use of low-dose psilocybin, which does not significantly alter cognition or perception. While low-dose psilocybin has garnered growing...