BACKGROUND: Over the past ten years, several psychedelic compounds, including tryptamines like lysergic acid diethylamide/LSD, psilocybin, ayahuasca, and dimethyltryptamine/DMT, have been tested in clinical trials for a range of psychiatric conditions, such as anxiety and depression. While these compounds are relatively available for treatment, ketamine and its S(+) enantiomer, esketamine, are...
Os transtornos de ansiedade e a compulsão alimentar representam desafios significativos para a saúde pública global, frequentemente associados a altos índices de resistência aos tratamentos convencionais. Diante desse cenário, este estudo tem como objetivo revisar as evidências científicas sobre o uso terapêutico de plantas psicodélicas — ayahuasca, psilocibina e jurema preta — no manejo da...
Background: Senior college students face a heightened risk of mental health problems, indicating the need for effective interventions. Mindfulness-based music therapy (MBMT) has been shown to improve mental health outcomes across various populations, yet evidence of its effectiveness in senior college students remains scarce. This randomized controlled trial aimed to test the efficacy of MBMT...
Bereavement and grief, particularly following natural disasters, can evoke a variety of painful emotions, including sadness and guilt. For some, particularly after a traumatic loss, the grieving process can become complicated, leading to significant distress. This paper explores the therapeutic function of grief dreams—dreams in which the deceased appears—as a tool for processing loss. Using a...
There has been a renewed interest in the use of various psychedelic agents as potential therapies for multiple psychiatric conditions, including post-traumatic stress disorder (PTSD), major depressive disorder (MDD), generalized anxiety disorder (GAD), to name a few. This follows the recent accumulation of evidence for ketamine pharmacotherapy and a rapid proliferation of clinics/programs...
BACKGROUND: Nightmares are a type of sleep disorder characterised by vivid and distressing dreams that cause abrupt awakenings, leading to significant discomfort. In adults, recurrent nightmares can negatively impact quality of life, daytime functioning, and overall mental health. In this context, it is essential to have valid, reliable, and culturally appropriate psychological instruments that...
Abstract: Yoga has transcended its traditional Indian roots to become a global therapeutic practice with measurable neurobiological effects. Emerging neuroscientific research demonstrates that yogic practices that comprising asana (postures), pranayama (breath regulation), and dhyana (meditation) induce structural and functional brain changes associated with improved mental health, emotional...
Introdução: O estresse crônico é um gatilho para doenças crônicas e transtornos mentais. Na Medicina do Estilo de Vida (MEV), práticas mente-corpo (mindfulness, yoga, meditação) são intervenções terapêuticas validadas com mecanismos neurobiológicos claros. Objetivos: Sintetizar as evidências de alto nível sobre a eficácia dessas práticas na redução do estresse e ansiedade em adultos, focando...
Stress is a major health issue in contemporary society, and mindfulness-based approaches reduce stress and anxiety but face practical barriers to consistent practice; this protocol evaluates a Virtual Reality (VR)-based observation meditation programme with an artificial intelligence (AI) coach ('Otti') that delivers real-time empathic, tailored prompts to support present-focused attention and...
Children with Tourette Syndrome (TS) commonly experience chronic motor and vocal tics, anxiety, and impaired daily functioning, underscoring the need for accessible, developmentally appropriate interventions. This study evaluated the effects of a 12-week movement-based mindfulness intervention-Mindful Energy Balance Exercise (MEBE)-on self-regulation in children with TS. A total of 135 children...