The recent mainstreaming of psychedelics has distanced itself from the countercultural image of the past, yet the question of whether psychedelics are political remains pressing. What happens when psychedelics meet politics?On one hand lies the politics of the unitive mystical experience: harmony, beyond good & evil, beyond space & time, and with love to all. Studying ayahuasca groups of...
Introduction Psychedelics have long been used in spiritual and medicinal contexts. Recently, growing scientific interest, driven by preliminary evidence of clinical efficacy, has renewed focus on their therapeutic potential. This study explores the historical evolution of clinical psychedelic research using a scientometric approach. Methods We downloaded 1664 documents from Scopus, covering the...
Recent studies indicate that mindfulness meditation may be beneficial for migraine symptoms; yet the potential of neurofeedback mindfulness meditation (NM) remains unexplored. This randomized controlled trial investigates the efficacy of NM compared to a controlled attention task for managing migraine. 101 adults with migraine participated in the study, wearing EEG headbands and engaging in...
Psychedelics were explored for their potential in the mental health field. However, research was delayed by concerns over short-term side effects and long-term consequences of substance use. Technological advances enabled the development of Hallucinatory Visual Virtual Experiences (HVVEs), namely psychedelic experiences simulations in immersive virtual reality. This study investigated HVVEs'...
Introduction Psychedelic Assisted Psychotherapy (PAP) has been legal in Switzerland since 2014 under supervised exceptional medical use with MDMA, LSD and Psilocybin with case by case authorisations delivered from the Federal Office of Public Health. In particular, since 2021, we have implemented a clinical activity at Geneva University Hospital (HUG) for treatment resistant patients using LSD...
Interessen for og bruken av psykedeliske stoffer vokser i befolkningen. Forskning har primært fokusert på terapeutiske anvendelser i formelle behandlingssettinger, og det er lite kunnskap om vedvarende negative effekter ved naturalistisk bruk. Målet med artikkelen er å gi en klinisk relevant oversikt over fenomenologi og symptombilde på langvarige psykiske plager etter bruk av psykedelika. Tre...
Stories of "mass hysteria" among teenage girls have often graced the headlines of Nepal's local and national newspapers, creating a public spectacle of a strange and mysterious form of affliction. Treatments include both shamanic rituals and psychosocial interventions, a new therapeutic modality that has gained prominence over the past two decades following the rise of global mental health....
Psychiatry ResearchDecember 1, 2025Ahmed Z Elmaadawi, Imane Naha, Shruti Prabhudesai et al.2 citations
Treatment-resistant depression (TRD) poses significant clinical challenges, often necessitating alternative treatments such as intravenous (IV) ketamine or intranasal esketamine. This study compared the effectiveness of these modalities and examined predictors of treatment response, including comorbidity profile, prior antidepressant failures, age, and gender. A retrospective chart review was...
CureusDecember 1, 2025Paweł Liszka, Agata Ogórek, Klaudia M Olejnik-Chlewicka et al.
Classic psychedelics and related substances, such as 3,4-methylenedioxymethamphetamine (MDMA), have again become a focus of interest in psychiatry as potential therapeutic tools. The aim of this paper is to review current data on their mechanisms of action, clinical applications in the treatment of mood and anxiety disorders, addictions and post-traumatic stress disorder (PTSD), as well as to...
Abstract Background Recent studies have highlighted the neuroprotective properties of certain mushrooms. Proposing a research hypothesis for a novel field of study into mitigating the neurological and neuropsychological symptoms associated with Alzheimer's disease (AD) and possible cure with natural methods. Psilocybe cubensis and Hericium erinaceus have proven to show therapeutic effects for...