Recent studies indicate that mindfulness meditation may be beneficial for migraine symptoms; yet the potential of neurofeedback mindfulness meditation (NM) remains unexplored. This randomized controlled trial investigates the efficacy of NM compared to a controlled attention task for managing migraine. 101 adults with migraine participated in the study, wearing EEG headbands and engaging in...
Sleep paralysis (SP) is a rapid-eye movement (REM) parasomnia in which a person is alert but temporarily unable to move or speak during the transition between wakefulness and sleep. It is a cardinal feature of narcolepsy; however, it may also occur independently as isolated sleep paralysis (ISP). This study examines ISP's prevalence, sociodemographic variations, and contributing factors,...
Mood disorders affect approximately one-third of individuals with epilepsy, posing an increased risk of suicide. There is an unquestionable need for more effective antidepressant treatment in this group of patients. This study explores the safety and tolerability of low-dose intravenous ketamine in six patients with comorbid depression and epilepsy. This report is limited to the post-hoc...
The authors present a case of an out-of- body experience (OBE) that occurred in a child with intractable epilepsy when stimulating the anterior insular cortex (AIC) by intracranial electrodes. After destroying several sites precisely located at the left AIC by radiofrequency thermocoagulation, the patient's seizures disappeared, and the OBE could not be reproduced when repeatedly stimulating...
The use of synthetic cannabinoids is becoming more widespread. Familiarity with the potential toxicities associated with these agents will grow in importance. We present a case of a woman who developed onset of confusion, visual hallucinations, and ataxia after vaporizing synthetic cannabinoids. MRI imaging demonstrated restricted diffusion and increased T2/FLAIR signal in the corpus callosum...
In the face of escalating recreational use of 'Ecstasy' (3,4-methylenedioxymethamphetamine, MDMA), physicians need to be aware of its possible adverse effects. We report two young patients who suffered subarachnoid haemorrhage following ingestion of 'Ecstasy' tablets. Angiographic studies demonstrated features consistent with vasculitis in both cases. Recognition of this association is...
Thomas Willis (1621-1675), author of the classical work Cerebri Anatome (1664), was arguably the father of the modern era of neurology. As compared with his neuroanatomy, relatively little attention has been paid to Willis' clinical neurology, as described in his Pathologiae Cerebri (1667) and De Anima Brutorum (1672), where he gave a structured account of disease of the nervous system as it...