BMC Palliative Care
July 6, 2017
Claudia L. Orellana‐Rios, Lukas Radbruch, Martina Kern et al.
162 citations
BACKGROUND: Maintaining a sense of self-care while providing patient centered care, can be difficult for practitioners in palliative medicine. We aimed to pilot an "on the job" mindfulness and compassion-oriented meditation training for interdisciplinary teams designed to reduce distress, foster resilience and strengthen a prosocial motivation in the clinical encounter. METHODS: Our objective...
Psychopharmacology
July 2017
Erin M Rock, Cheryl L Limebeer, Gavin N Petrie et al.
Cannabis is commonly used by humans to relieve stress. Here, we evaluate the potential of intraperitoneally (i.p.) administered Δ9-tetrahydrocannabiol (THC) and cannabidiolic acid (CBDA, the precursor of cannabidiol [CBD]) to produce dose-dependent effects on anxiety-like responding in the light-dark (LD) emergence test of anxiety-like responding in rats, when administered acutely or...
Holistic Nursing Practice
July 1, 2017
Pilar Gracia-Gracia, Bárbara Oliván-Blázquez
Nursing staff has been identified as one of the main risk groups for the development of burnout. The objective of this study is to analyze the ability of self-compassion mindfulness related to burnout in nurses of intensive care units. The results show that the level of burnout of nursing staff is inversely related to their level of self-compassion.
Pharmacological Research
July 2017
Carola Rong, Yena Lee, Nicole E Carmona et al.
The high and increasing prevalence of medical marijuana consumption in the general population invites the need for quality evidence regarding its safety and efficacy. Herein, we synthesize extant literature pertaining to the phytocannabinoid cannabidiol (CBD) and its brain effects. The principle phytocannabinoid Δ9-tetrahydrocannabinol (Δ9-THC) and CBD are the major pharmacologically active...
Psychopharmacology
July 1, 2017
Anya K. Bershad, Melissa A. Miller, Harriet de Wit
12 citations
Rationale ±3,4-Methylenedioxymethamphetamine (MDMA, “ecstasy”) is a stimulant-psychedelic drug with unique social effects. It may dampen reactivity to negative social stimuli such as social threat and rejection. Perhaps because of these effects, MDMA has shown promise as a treatment for post-traumatic stress disorder (PTSD). However, the effect of single doses of MDMA on responses to an acute...
Fortschritte der Neurologie · Psychiatrie
July 1, 2017
Tomislav Majić, Henrik Jungaberle, Timo Torsten Schmidt et al.
10 citations
Zusammenfassung Hintergrund Der Einsatz von serotonergen Halluzinogenen (Psychedelika) wie Lysergsäure-Diethylamid (LSD) und Psilocybin und Entaktogenen wie 3,4-Methylendioxymethamphetamin (MDMA) im Rahmen von Psychotherapie ist in den letzten Jahren wieder zunehmend ins Licht des wissenschaftlichen Interesses gerückt. Die vorliegende Arbeit fasst die aktuelle Evidenz zur substanzunterstützten...
Journal of Humanistic Psychology
June 14, 2017
Thomas Cody Swift, Alexander Belser, Gabrielle Agin-Liebes et al.
187 citations
Recent randomized controlled trials of psilocybin-assisted psychotherapy for patients with cancer suggest that this treatment results in large-magnitude reductions in anxiety and depression as well as improvements in attitudes toward disease progression and death, quality of life, and spirituality. To better understand these findings, we sought to identify psychological mechanisms of action...
Sleep Medicine Reviews
June 8, 2017
Dan Denis, Christopher C. French, Alice M. Gregory
129 citations
Sleep paralysis is a relatively common but under-researched phenomenon. While the causes are unknown, a number of studies have investigated potential risk factors. In this article, we conducted a systematic review on the available literature regarding variables associated with both the frequency and intensity of sleep paralysis episodes. A total of 42 studies met the inclusion criteria. For...
Behaviour Research and Therapy
June 3, 2017
P. Goldin, A. Morrison, Hooria Jazaieri et al.
Cognitive-Behavioral Group Therapy (CBGT) and Mindfulness-Based Stress Reduction (MBSR) are efficacious in treating social anxiety disorder (SAD). It is not yet clear, however, whether they share similar trajectories of change and underlying mechanisms in the context of SAD. This randomized controlled study of 108 unmedicated adults with generalized SAD investigated the impact of CBGT vs. MBSR...
Frontiers in Pharmacology
May 11, 2017
Antônio Waldo Zuardi, Natália Pegoraro Rodrigues, Angélica L. Silva et al.
292 citations
The purpose of this study was to investigate whether the anxiolytic effect of cannabidiol (CBD) in humans follows the same pattern of an inverted U-shaped dose-effect curve observed in many animal studies. Sixty healthy subjects of both sexes aged between 18 and 35 years were randomly assigned to five groups that received placebo, clonazepam (1 mg), and CBD (100, 300, and 900 mg). The subjects...
Journal of Psychoactive Drugs
May 8, 2017
Kelan Thomas, Benjamin Malcolm, Dan Lastra
77 citations
Recent research suggests that functional connectivity changes may be involved in the pathophysiology of psychiatric disorders. Hyperconnectivity in the default mode network has been associated with psychopathology, but psychedelic serotonin agonists like psilocybin may profoundly disrupt these dysfunctional neural network circuits and provide a novel treatment for psychiatric disorders. We have...
The Journal of Alternative and Complementary Medicine
May 2017
Gisela Boxleitner, Shelley Jolie, Dana Shaffer et al.
Radiation treatment for head and neck cancer introduces adaptive demands and subjects patients to significant and unique psychosocial challenges. There is growing evidence that meditation is useful in lessening anxiety and depression in cancer patients. This study compared the effects of two types of meditation training on the psychological responses of patients with head and neck cancer during...
Research in Developmental Disabilities
May 2017
Bram Sizoo, Erik Kuiper
Anxiety and depression co-occur in 50-70% of adults with autism spectrum disorder (ASD) but treatment methods for these comorbid problems have not been systematically studied. Recently, two ASD-tailored protocols were published: mindfulness based stress reduction (MBSR) and cognitive behavioural therapy (CBT). We wanted to investigate if both methods are equally effective in reducing anxiety...
Consciousness and Cognition
May 2017
Mengran Xu, Christine Purdon, Paul Seli et al.
Mind wandering can be costly, especially when we are engaged in attentionally demanding tasks. Preliminary studies suggest that mindfulness can be a promising antidote for mind wandering, albeit the evidence is mixed. To better understand the exact impact of mindfulness on mind wandering, we had a sample of highly anxious undergraduate students complete a sustained-attention task during which...
April 30, 2017
S. Mohamadpour, F. Tajikzadeh, A. Aflakseir
Objective: The aim of the present study was to investigate the efficacy of mindfulness-based cognitive therapy (MBCT) on self-efficacy and anxiety among epileptic patients. Methods: The present study with a pretest-posttest control-group design was performed on epileptic patients in public healthcare centers of Kuhdasht, Iran. Through randomized sampling, 15 patients were selected for the...
Sleep
April 28, 2017
Cristina Banu, Pierre McDuff, Antonio Zadra
1 citation
The present study tested a prediction from Levin and Nielsen’s (2007) neurocognitive model of disturbed dreaming stipulating that variations in the frequency of bad dreams and nightmares are partly determined by day-to-day variations in emotional stress. The model also suggests that relations between dreams and stress may vary as a function of personality traits. 224 adults (186F, 38M, mean...
European Journal of Integrative Medicine
April 28, 2017
Kristoffer Jonsson, Anette Kjellgren
15 citations
Among the anxiety disorders Generalized Anxiety Disorder (GAD) is currently the most treatment resistant, suggesting that treatment protocols could be enhanced. A promising treatment of GAD is flotation-REST (Restricted Environmental Stimulation Technique), which in earlier studies has been shown to alleviate symptoms in GAD. Although, research on flotation-REST as a treatment of GAD has shown...
Neuropsychopharmacology
April 27, 2017
Matthias E. Liechti
230 citations
All modern clinical studies using the classic hallucinogen lysergic acid diethylamide (LSD) in healthy subjects or patients in the last 25 years are reviewed herein. There were five recent studies in healthy participants and one in patients. In a controlled setting, LSD acutely induced bliss, audiovisual synesthesia, altered meaning of perceptions, derealization, depersonalization, and mystical...
April 20, 2017
N. Wongtongkam, Branka Krivokapic‐Skoko, R. Duncan et al.
Abstract Workplace mindfulness is a recognised tool for enhancing health and well-being of university staff and may result in better task performance and satisfaction in the workplace. The study examined the beneficial effects of mindfulness meditation on job satisfaction, mindful awareness and anxiety levels in university personnel. Mixed methods with a quasi-experiment and in-depth interviews...
Neurology
April 18, 2017
D. Wheelwright, N. Dangayach, Stephen Griffiths et al.
Objective: We hypothesize that intra-ICU initiation of guided mindfulness meditation is feasible and will help prevent the development of anxiety and depression in good grade SAH patients. Background: Aneurysmal Subarachnoid Hemorrhage (SAH) has a case fatality rate of about 20%. Of all SAH patients, 40% are “good grade” defined as Hunt-Hess 1–2 with normal mental status whereas 60% are poor...